Validation of The Individualized Neuromuscular Quality of Life in Japanese patients with myotonic dystrophy
Validation of The Individualized Neuromuscular Quality of Life in Japanese patients with myotonic dystrophy
复制标题
DOI：
10.1002/mus.26071
复制
发表时间：
2018-07-01
期刊：
影响因子：
3.4
通讯作者：
Matsumura, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Fujino, Haruo;Saito, Toshio;Matsumura, Tsuyoshi
简介：个体化神经肌肉生活质量（INQoL）用于测量神经肌肉疾病患者的生活质量（QoL）。我们进行了这项研究，翻译和验证强直性肌营养不良患者的INQoL的日语版本。方法：进行正向和反向翻译、患者测试和心理测量验证。我们使用36项简明健康调查表（SF-36）和修改后的兰金量表进行同步验证。结果：对90名成人患者进行了日本INQoL。大部分领域的内部一致性和重测信度都很高（Cronbach系数为0.88-0.96，组内系数为0.64-0.99）。INQoL领域与相关SF-36子量表中度至高度相关（斯皮尔曼-0.23至-0.74）。症状严重程度、病程、就业状况和呼吸机使用影响总体生活质量。讨论：INQoL是日本强直性肌营养不良患者QoL的可靠且经验证的指标。肌肉神经58：56 - 63，2018
Introduction: The Individualized Neuromuscular Quality of Life (INQoL) is used to measure the quality of life (QoL) of patients with neuromuscular disease. We conducted this study to translate and validate the Japanese version of the INQoL in patients with myotonic dystrophy. Methods: Forward and backward translation, patient testing, and psychometric validation were performed. We used the 36-Item Short Form Health Survey (SF-36) and the modified Rankin scale for concurrent validation. Results: The Japanese INQoL was administered to 90 adult patients. The coefficients for internal consistency and test-retest reliability were adequately high in most domains (Cronbach 0.88-0.96 and intraclass coefficient 0.64-0.99). INQoL domains were moderately to strongly associated with relevant SF-36 subscales (Spearman's -0.23 to -0.74). Symptom severity, disease duration, employment status, and use of a ventilator influenced overall QoL. Discussion: The INQoL is a reliable and validated measure of QoL for Japanese patients with myotonic dystrophy. Muscle Nerve58: 56-63, 2018