PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis.

PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis.
复制标题

DOI:
10.1016/j.placenta.2020.10.029
复制
发表时间:
2021-01-01
期刊:
影响因子:
3.8
通讯作者:
Tuteja G
Tuteja G
中科院分区:
医学3区
文献类型:
--
作者:
Jain A;Tuteja G

文献摘要

参考文献

被引文献

相似文献

单细胞rna测序(scRNA-Seq)提高了我们对人类胎盘中单个细胞类型的理解。然而,当试图了解模型系统中的表达模式如何与妊娠早期人类胎盘的表达模式相对应时,胎盘scRNA-Seq数据并不容易获得。因此,我们开发了PlacentaCellEnrich,这是一个工具,它将基因集作为输入,然后根据人胎盘scRNA-Seq数据报告输入集是否富集了具有胎盘细胞特异性表达模式的基因。PlacentaCellEnrich工具可以在https://placentacellenrich.gdcb.iastate.edu/上免费获得,根据麻省理工学院的许可用于非营利学术用途。
Single-cell RNA-Sequencing (scRNA-Seq) has improved our understanding of individual cell types in the human placenta. However, placental scRNA-Seq data is not readily accessible when trying to understand how expression patterns in model systems correspond to those from first trimester human placenta. Therefore, we developed PlacentaCellEnrich, a tool that takes a gene set as input, and then reports if the input set is enriched for genes with placenta cell-specific expression patterns, based on human placenta scRNA-Seq data. The PlacentaCellEnrich tool is freely available at https://placentacellenrich.gdcb.iastate.edu/ for non-profit academic use under the MIT license.
DOI: 10.1016/j.placenta.2015.11.001
发表时间: 2016-01
期刊: Placenta
影响因子: 3.8
作者:
Tuteja G;Chung T;Bejerano G
通讯作者: Bejerano G
DOI: 10.1038/s41598-017-17614-5
发表时间: 2017-12-08
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Jain, Ashish;Ezashi, Toshihiko;Tuteja, Geetu
通讯作者: Tuteja, Geetu
DOI: 10.1038/s41586-018-0698-6
发表时间: 2018-11
期刊: Nature
影响因子: 64.8
作者:
Vento-Tormo R;Efremova M;Botting RA;Turco MY;Vento-Tormo M;Meyer KB;Park JE;Stephenson E;Polański K;Goncalves A;Gardner L;Holmqvist S;Henriksson J;Zou A;Sharkey AM;Millar B;Innes B;Wood L;Wilbrey-Clark A;Payne RP;Ivarsson MA;Lisgo S;Filby A;Rowitch DH;Bulmer JN;Wright GJ;Stubbington MJT;Haniffa M;Moffett A;Teichmann SA
通讯作者: Teichmann SA
DOI: 10.3389/fendo.2018.00570
发表时间: 2018
影响因子: 5.2
作者:
Woods L;Perez-Garcia V;Hemberger M
通讯作者: Hemberger M
DOI: 10.1038/s41596-020-0292-x
发表时间: 2020-02-26
期刊: NATURE PROTOCOLS
影响因子: 14.8
作者:
Efremova, Mirjana;Vento-Tormo, Miquel;Vento-Tormo, Roser
通讯作者: Vento-Tormo, Roser