PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis.
PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis.
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DOI:
10.1016/j.placenta.2020.10.029
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发表时间:
2021-01-01
期刊:
影响因子:
3.8
通讯作者:
Tuteja G
中科院分区:
文献类型:
--
作者:
Jain A;Tuteja G
Single-cell RNA-Sequencing (scRNA-Seq) has improved our understanding of individual cell types in the human placenta. However, placental scRNA-Seq data is not readily accessible when trying to understand how expression patterns in model systems correspond to those from first trimester human placenta. Therefore, we developed PlacentaCellEnrich, a tool that takes a gene set as input, and then reports if the input set is enriched for genes with placenta cell-specific expression patterns, based on human placenta scRNA-Seq data. The PlacentaCellEnrich tool is freely available at https://placentacellenrich.gdcb.iastate.edu/ for non-profit academic use under the MIT license.
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