Potential of APDM mobility lab for the monitoring of the progression of Parkinson's disease.
Potential of APDM mobility lab for the monitoring of the progression of Parkinson's disease.
复制标题
DOI：
10.1586/17434440.2016.1153421
复制
发表时间：
2016-05
影响因子：
3.1
通讯作者：
Horak FB
中科院分区：
文献类型：
--
作者：
Mancini M;Horak FB
APDM的移动实验室系统提供便携式，经过验证的，可靠的，客观的平衡和步态测量，对PD敏感。在这篇综述中，我们描述了使用移动实验室系统收集的客观测量值用于跟踪PD纵向进展的潜力。平衡和步态是影响PD患者生活质量的最重要的运动障碍之一。Mobility Lab在规定的任务（如仪器化起床和行走测试或安静站立）中，在腿部、躯干和手臂上使用身体佩戴的Opal传感器，以快速量化临床环境中的平衡和步态质量。同样的Opal传感器可以与患者一起送回家，以持续监测他们的日常活动质量。客观的措施有可能在整个过程中监测PD中移动障碍的进展，以改善患者护理并加速临床试验。
APDM’s Mobility Lab system provides portable, validated, reliable, objective measures of balance and gait that are sensitive to PD. In this review, we describe the potential of objective measures collected with the Mobility Lab system for tracking longitudinal progression of PD. Balance and gait are among the most important motor impairments influencing quality of life for people with PD. Mobility Lab uses body-worn, Opal sensors on the legs, trunk and arms during prescribed tasks, such as the instrumented Get Up and Go test or quiet stance, to quickly quantify the quality of balance and gait in the clinical environment. The same Opal sensors can be sent home with patients to continuously monitor the quality of their daily activities. Objective measures have the potential to monitor progression of mobility impairments in PD throughout its course to improve patient care and accelerate clinical trials.