Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.
Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.
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DOI：
10.1172/jci21748
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发表时间：
2004-05
期刊：
影响因子：
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通讯作者：
N. Freedman;R. Lefkowitz
中科院分区：
文献类型：
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作者：
N. Freedman;R. Lefkowitz
Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.
