A comparison of US and Australian men's values and preferences for PSA screening.
A comparison of US and Australian men's values and preferences for PSA screening.
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DOI：
10.1186/1472-6963-13-388
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发表时间：
2013-10-05
影响因子：
2.8
通讯作者：
Pignone MP
中科院分区：
文献类型：
--
作者：
Howard K;Brenner AT;Lewis C;Sheridan S;Crutchfield T;Hawley S;Nielsen ME;Pignone MP
从价值观评估中得出的患者偏好有助于为筛查计划的设计提供信息，但如何最好地做到这一点，以及这种偏好在跨国之间是否存在差异，尚未得到充分研究。本研究的目的是比较澳大利亚和美国男性对 PSA（前列腺特异性抗原）筛查的价值观和偏好。我们对 50-75 岁、无前列腺癌个人或家族史的男性进行了一项基于互联网的调查，这些男性是从美国和澳大利亚的一家调查研究组织的在线小组中招募的。参与者查看有关前列腺癌和通过 PSA 检测进行前列腺癌筛查的信息，然后完成一项价值观澄清任务，其中包括 4 个关键属性的信息：1) 被诊断患有前列腺癌，2) 死于前列腺癌，3) 由于筛查而需要活检，以及 4) 由于筛查而出现阳痿或失禁。结果测量是自我报告的最重要属性、未标记的筛选测试选择和标记的筛选意图，并在任务后问卷中进行评估。我们招募了 911 名参与者（美国：456；澳大利亚：455），平均年龄为 59.7 岁； 88.0% 是白人； 36.4% 至少完成了学士学位； 42.0% 的受访者表示在过去 12 个月内进行过 PSA 测试。澳大利亚男性更有可能是白人并且最近接受过筛查。对于美国和澳大利亚男性来说，最重要的属性是死于前列腺癌的机会。与美国 (26.3%) 参与者相比，澳大利亚 (39.1%) 参与者对未标记的任务后类似 PSA 筛查的偏好更大（调整后 OR 1.68 (1.28-2.22)）。这两个国家的筛查意向都很高：美国：73.7%，澳大利亚：78.0% (p = 0.308)。美国和澳大利亚男性对 PSA 筛查的意愿很高；在每个国家，在未标记的问题上选择类似 PSA 的选项的男性人数都较少。澳大利亚男性更倾向于 PSA 筛查。两国男性并不认为诊断风险增加是一个负面因素，这表明需要做更多的工作来向面临 PSA 筛查决定的男性传达过度诊断的概念。该试验已在 ClinicalTrials.gov 上注册 (NCT01558583)。
Patient preferences derived from an assessment of values can help inform the design of screening programs, but how best to do so, and whether such preferences differ cross-nationally, has not been well-examined. The objective of this study was to compare the values and preferences of Australian and US men for PSA (prostate specific antigen) screening. We used an internet based survey of men aged 50–75 with no personal or family history of prostate cancer recruited from on-line panels of a survey research organization in the US and Australia. Participants viewed information on prostate cancer and prostate cancer screening with PSA testing then completed a values clarification task that included information on 4 key attributes: chance of 1) being diagnosed with prostate cancer, 2) dying from prostate cancer, 3) requiring a biopsy as a result of screening, and 4) developing impotence or incontinence as a result of screening. The outcome measures were self reported most important attribute, unlabelled screening test choice, and labelled screening intent, assessed on post-task questionnaires. We enrolled 911 participants (US:456; AU:455), mean age was 59.7; 88.0% were white; 36.4% had completed at least a Bachelors’ degree; 42.0% reported a PSA test in the past 12 months. Australian men were more likely to be white and to have had recent screening. For both US and Australian men, the most important attribute was the chance of dying from prostate cancer. Unlabelled post-task preference for the PSA screening-like option was greater for Australian (39.1%) compared to US (26.3%) participants (adjusted OR 1.68 (1.28-2.22)). Labelled intent for screening was high for both countries: US:73.7%, AUS:78.0% (p = 0.308). There was high intent for PSA screening in both US and Australian men; fewer men in each country chose the PSA-like option on the unlabelled question. Australian men were somewhat more likely to prefer PSA screening. Men in both countries did not view the increased risk of diagnosis as a negative aspect, suggesting more work needs to be done on communicating the concept of overdiagnosis to men facing a PSA screening decision. This trial was registered at ClinicalTrials.gov (NCT01558583).
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影响因子：
39.2
作者：
Moyer, Virginia A.
通讯作者：
Moyer, Virginia A.
影响因子：
--
作者：
Hoffman, Richard M.;Couper, Mick P.;Barry, Michael J.
通讯作者：
Barry, Michael J.
DOI：
10.1056/nejmoa0810696
发表时间：
2009-03-26
期刊：
The New England journal of medicine
影响因子：
--
作者：
Andriole GL;Crawford ED;Grubb RL 3rd;Buys SS;Chia D;Church TR;Fouad MN;Gelmann EP;Kvale PA;Reding DJ;Weissfeld JL;Yokochi LA;O'Brien B;Clapp JD;Rathmell JM;Riley TL;Hayes RB;Kramer BS;Izmirlian G;Miller AB;Pinsky PF;Prorok PC;Gohagan JK;Berg CD;PLCO Project Team
通讯作者：
PLCO Project Team
影响因子：
--
作者：
Howard, Kirsten;Barratt, Alex;Patel, Manish I.
通讯作者：
Patel, Manish I.
影响因子：
105.7
作者：
Hersch, Jolyn;Jansen, Jesse;McCaffery, Kirsten
通讯作者：
McCaffery, Kirsten