Bovine leukemia virus post-envelope gene coded protein: evidence for expression in natural infection.
Bovine leukemia virus post-envelope gene coded protein: evidence for expression in natural infection.
复制标题
牛白血病病毒后包膜基因编码蛋白：自然感染中表达的证据。
DOI：
10.1016/0006-291x(85)91809-1
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发表时间：
1985
影响因子：
3.1
通讯作者：
Oroszlan,S
中科院分区：
文献类型：
--
作者：
Yoshinaka,Y;Oroszlan,S
Partial sequence analysis of a 14 kilodalton protein (p14), synthesized by in vitro translation of bovine leukemia virus genomic RNA, showed that it is encoded in the ‘X’region of proviral DNA, located between the env gene and the 3′ long terminal repeat. The ‘X’gene contains a short and a long open reading frame (X-SORF and X-LORF) which overlap. BLV p14 x is specified by X-SORF and not X-LORF as seen with the related human T-cell leukemia virus which expresses p38-40 x. Antibodies in sera from animals with BLV induced tumors were shown to recognize p14 x. Expression of this protein in natural infection might be important for virus replication and/or for BLV induced oncogenesis.
