It's a kar9ochore to capture microtubules
It's a kar9ochore to capture microtubules
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DOI：
10.1038/35014089
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发表时间：
2000-06-01
影响因子：
21.3
通讯作者：
Bloom, K
中科院分区：
文献类型：
--
作者：
Bloom, K
微管对皮质空间线索的定向对于不对称细胞突起的保真度至关重要。现在已经在酵母中发现了一个由Bim1和Kar9组成的皮质微管捕获部位。BIM1是EB1的酵母同源物，EB1是腺瘤性息肉病结肠(APC)的结合伙伴，这表明该复合体的重要特征可能是高度保守的。
Microtubule orientation to cortical spatial cues is essential for the fidelity of asymmetric cellular processes. A cortical microtubule-capture site, composed of Bim1 and Kar9, has now been identified in yeast. Bim1 is the yeast homologue of EB1, a binding partner of the adenomatous polyposis coli (APC), indicating that important features of this complex may be highly conserved.