HIV drug resistance in various body compartments.
HIV drug resistance in various body compartments.
复制标题
身体各个部位的艾滋病毒耐药性。
DOI：
10.1097/coh.0000000000000741
复制
发表时间：
2022
影响因子：
4.1
通讯作者：
Kearney,MaryF
中科院分区：
文献类型：
--
作者：
vanZyl,GertU;Dorfman,JeffreyR;Kearney,MaryF
Drug-resistant variants, which may be selected in tissues under conditions of variable adherence and drug penetration, appear to disseminate quickly, and become detectable in blood. This may explain why drug resistance discordance between plasma and these compartments is rarely found. Partial compartmentalization of HIV populations is well established for the CSF and the genital tract but other than blood plasma, evidence is lacking to support drug resistance testing in body compartments.
