Neural activation during response competition
Neural activation during response competition
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DOI：
10.1162/089892900563984
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发表时间：
2000-01-01
影响因子：
3.2
通讯作者：
Gabrieli, JDE
中科院分区：
文献类型：
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作者：
Hazeltine, E;Poldrack, R;Gabrieli, JDE
由Eriksen和Eriksen [Eriksen，B.一、和埃里克森角，澳-地W.（1974年）。噪声字母对非搜索任务中目标字母识别的影响。Perception C Psychophysics，16，143-149]，提供了一种手段，选择性地操纵反应竞争的存在或不存在，同时保持其他任务需求不变。我们使用功能性磁共振成像（fMRI）测量大脑活动在执行侧翼任务。根据以前的行为研究，试验中，侧翼刺激表明一个不同的反应比中央刺激进行显着更慢的试验中，所有的刺激表明相同的反应。这种反应时间效应伴随着四个区域的活动增加：右腹外侧前额叶皮层、辅助运动区、左上级顶叶和左前顶叶皮层。这种增加并不是由于刺激复杂性的变化，也不是由于需要克服以前学习到的刺激和反应之间的联系。本研究和其他操纵反应干扰的实验之间的对应关系表明，额叶焦点可能与反应抑制过程有关，而后部焦点可能与不适当反应的表征的激活有关。
The flanker task, introduced by Eriksen and Eriksen [Eriksen, B. A., & Eriksen, C. W. (1974). Effects of noise letters upon the identification of a target letter in a nonsearch task. Perception C Psychophysics, 16, 143-149], provides a means to selectively manipulate the presence or absence of response competition while keeping other task demands constant. We measured brain activity using functional magnetic resonance imaging (fMRI) during performance of the flanker task. In accordance with previous behavioral studies, trials in which the flanking stimuli indicated a different response than the central stimulus were performed significantly more slowly than trials in which all the stimuli indicated the same response. This reaction time effect was accompanied by increases in activity in four regions: the right ventrolateral prefrontal cortex, the supplementary motor area, the left superior parietal lobe, and the left anterior parietal cortex. The increases were not due to changes in stimulus complexity or the need to overcome previously learned associations between stimuli and responses. Correspondences between this study and other experiments manipulating response interference suggest that the frontal foci may be related to response inhibition processes whereas the posterior foci may be related to the activation of representations of the inappropriate responses.