Serological surveillance reveals widespread influenza A H7 and H9 subtypes among chicken flocks in Egypt
Serological surveillance reveals widespread influenza A H7 and H9 subtypes among chicken flocks in Egypt
复制标题
DOI：
10.1007/s11250-012-0243-9
复制
发表时间：
2013-02-01
影响因子：
1.7
通讯作者：
Abddel-Moneim, Ahmed Sayed
中科院分区：
文献类型：
--
作者：
Afifi, Manal A. A.;El-Kady, Magdy F.;Abddel-Moneim, Ahmed Sayed
多种禽流感病毒亚型在世界范围内流行，对人类构成严重威胁，被认为是导致人类流感大流行的关键因素。本研究旨在确定埃及鸡群中H7和H9禽流感感染的潜在存在。从经历呼吸窘迫和/或可变死亡率的鸡群中收集血清样品。用鸡红细胞血凝抑制试验筛选H7和H9病毒感染。从9个肉鸡群、12个种鸡群和18个蛋鸡群采集血清样品。在1，225份受检血清中，分别有14个鸡群和21个鸡群的417份（34%）和605份（49.4%）对H7和H9呈阳性反应。H7和H9抗体的流行率在蛋鸡中较高，其次是种鸡，然后是肉鸡群。应特别考虑在埃及控制流感病毒，因为由于存在亚临床感染，大流行性流感毒株可能会在不知不觉中发展，而且确实存在与埃及流行的地方性H5 N1病毒毒株重新组合的可能性。
Multiple avian influenza viruses' subtypes are circulating worldwide possessing serious threat to human populations and considered key contributors to the emergence of human influenza pandemics. This study aimed to identify the potential existence of H7 and H9 avian influenza infections circulating among chicken flocks in Egypt. Serum samples were collected from chicken flocks that experienced respiratory distresses and/or variable mortality rates. H7 and H9 virus infections were screened by haemagglutination inhibition assay using chicken erythrocytes. Serum samples were collected from 9 broiler, 12 breeder and 18 layer flocks. Out of 1,225 examined sera, 417 (34 %) from 14 flocks and 605 (49.4 %) from 21 flocks were found positive for H7 and H9, respectively. Prevalence of both H7 and H9 antibodies were higher in layer followed by breeder then broiler flocks. Special consideration should be paid to control influenza viruses in Egypt, as pandemic influenza strains may develop unnoticed given the presence of subclinical infections, and the possibility of re-assortment with the prevailing endemic H5N1 virus strains in Egypt do exist.