Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions
Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions
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DOI：
10.1126/science.276.5310.245
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发表时间：
1997-04-11
期刊：
影响因子：
56.9
通讯作者：
Wachtershauser, G
中科院分区：
文献类型：
--
作者：
Huber, C;Wachtershauser, G
在模拟水热温度下还原性乙酰辅酶 A 途径反应的实验中，发现共沉淀 NiS 和 FeS 的水浆将 CO 和 CH3SH 转化为活化的硫酯 CH3-CO-SCH3，后者水解为乙酸。在苯胺存在下，形成乙酰苯胺。当 NiS-FeS 用催化量的硒进行改性时，仅由 CO 和 H2S 形成乙酸和 CH3SH。该反应可以被认为是化学自养生命起源的原始引发反应。
In experiments modeling the reactions of the reductive acetyl-coenzyme A pathway at hydrothermal temperatures, it was found that an aqueous slurry of coprecipitated NiS and FeS converted CO and CH3SH into the activated thioester CH3-CO-SCH3, which hydrolyzed to acetic acid. In the presence of aniline, acetanilide was formed. When NiS-FeS was modified with catalytic amounts of selenium, acetic acid and CH3SH were formed from CO and H2S alone. The reaction can be considered as the primordial initiation reaction for a chemoautotrophic origin of life.