Comparación cefalométrica entre un paciente acromegálico y su hermano gemelo
Comparación cefalométrica entre un paciente acromegálico y su hermano gemelo
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肩胛骨与双子的头颅测量比较
DOI：
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
A. Díaz
中科院分区：
文献类型：
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作者：
Tomás Freundlich;David Arueste;G. Manríquez;A. Díaz
肢端肥大症是一种以生长激素 (GH) 和胰岛素样生长因子 1 (IGF-1) 过度产生引起的缓慢进展的躯体畸形为特征的疾病，主要与垂体腺瘤有关。面部最明显的表现是由于下颌过度生长而导致下颌前突。这项工作的目的是通过头影测量分析和头影测量叠加，对诊断为肢端肥大症的患者与其未患有该病的双胞胎兄弟进行颅面形态学比较。我们的结果表明，肢端肥大症患者的蝶鞍尺寸显着增加，上颌骨和下颌骨前移，下颌位移更加明显。肢端肥大症中下颌骨的形态变化主要归因于髁突单位的增加导致下颌升支的生长。
Acromegaly is a disease characterized by a slowly progressive somatic disfigurement caused by the overproduction of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), mainly associated with a pituitary adenoma. The most evident manifestation at the facial level is a mandibular prognathism due to excess growth of the jaw. The purpose of this work was to perform a craniofacial morphological comparison through cephalometric analysis and cephalometric superimposition between a patient diagnosed with acromegaly and his twin brother who does not have the disease. Our results showed that in the acromegalic patient there is a significant increase in the size of the sella turcica, an anterior displacement of the maxilla and mandible, being the mandibular displacement more marked. The morphological change experienced by the mandible in acromegaly is mainly attributed to the growth of the mandibular ramus due to an increase in the condylar unit.