Intracranial hypertension in relation to memory functioning during the first year after severe head injury.
Intracranial hypertension in relation to memory functioning during the first year after severe head injury.
复制标题
严重颅脑损伤后第一年颅内高压与记忆功能的关系。
DOI：
10.1097/00006123-199102000-00004
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发表时间：
1991
期刊：
影响因子：
4.8
通讯作者：
Portman,SM
中科院分区：
文献类型：
--
作者：
Levin,HS;Eisenberg,HM;Gary,HE;Marmarou,A;Foulkes,MA;Jane,JA;Marshall,LF;Portman,SM
使用创伤性昏迷数据库获得的6个月和1年神经行为结局数据，评估闭合性颅脑损伤后颅内高压与残余记忆缺陷的关系。用颅内压超过20 mm Hg的时间百分比和损伤后72小时内记录的最大值来分析颅内压。记忆测量包括损伤后6个月（n= 149）和1年（n= 132）获得的单词列表回忆、散文回忆和设计的视觉记忆。在创伤性昏迷数据库的队列中，超过一半符合神经行为随访研究标准的患者出现颅内高压。线性回归分析显示，颅内压升高对6个月时的一些记忆测量有影响，但不是全部，而对1年的随访检查结果为阴性。我们的结论是，颅内压升高对后来的记忆功能几乎没有影响，而且在严重颅脑损伤的幸存者中，颅内压升高的影响在一年后会减弱。（神经外科28:196- 200,1991）
: The relationship between intracranial hypertension and residual memory deficit after closed head injury was evaluated using the 6-month and 1-year neurobehavioral outcome data obtained by the Traumatic Coma Data Bank. Intracranial pressure was analyzed using the percentage of time that it exceeded 20 mm Hg and the maximum value recorded during the first 72 hours after injury. Memory measures included recall of word lists, prose recall, and visual memory for designs that were obtained 6 months (n= 149) and 1 year (n= 132) after injury. Intracranial hypertension occurred in more than half of the Traumatic Coma Data Bank cohort who met the criteria for the neurobehavioral follow-up study. Linear regression analysis disclosed an effect of elevated intracranial pressure on some, but not all, measures of memory at 6 months, whereas the results were negative for the 1-year follow-up examination. We conclude that the elevation of intracranial pressure exerts little if any effect on later memory functioning, and that any effect it does have diminishes over 1 year in survivors of severe head injury.(Neurosurgery 28: 196-200, 1991)