Modeling the pH-dependent PLA oligomer degradation kinetics
Modeling the pH-dependent PLA oligomer degradation kinetics
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DOI：
10.1016/j.polymdegradstab.2014.08.012
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发表时间：
2014-12-01
影响因子：
5.9
通讯作者：
Moscatelli, D.
中科院分区：
文献类型：
--
作者：
Lazzari, S.;Codari, R.;Moscatelli, D.
乳酸低聚物的水解涉及几种不同的反应，酸催化的、碱催化的以及非催化的。在本文中，pH依赖的动力学模型已被开发和其动力学常数通过拟合的实验数据，降解乳酸低聚物在水溶液中，在pH = 1，2，3.5，5.7和7.4，在37 ℃进行评估。该模型能够正确地描述实验数据，平均误差约为5%。在选定温度下的动力学常数的估计值为：k（D）（α）= 4.44 x 10（-3）L（2）mol（-2）h（-1），k（D）（β）= 9.29 x 10（-4）L（2）mol（-2）h（-1）（酸催化），k（RH）= 1.56 x 10（3）L（2）mol（-2）h（-1），k（BB）= 2.88 x 10（6）Lmol（-1）h（-1）（碱催化）和k（w）= 2.49 x 10（-5）Lmol（-1）h（-1）（非催化）。(C)2014爱思唯尔有限公司版权所有。
The hydrolysis of lactic acid oligomers involves several different reactions, acid-catalyzed, base-catalyzed as well as non-catalyzed. In the present paper a pH-dependent kinetic model has been developed and its kinetic constants evaluated by fitting to experimental data of degrading lactic acid oligomers at 37 degrees C in aqueous solution at pH = 1, 2, 3.5, 5.7 and 7.4. The model was able to properly describe the experimental data with an average error of about 5%. The estimated values of the kinetic constants at the selected temperature are: k(D)(alpha) = 4.44 x 10(-3) L(2)mol(-2)h(-1), k(D)(beta) = 9.29 x 10(-4) L(2)mol(-2)h(-1) (acid-catalyzed), k(RH) = 1.56 x 10(3) L(2)mol(-2)h(-1), k(BB) = 2.88 x 10(6) Lmol(-1)h(-1) (base-catalyzed) and k(w) = 2.49 x 10(-5) Lmol(-1)h(-1) (non-catalyzed). (C) 2014 Elsevier Ltd. All rights reserved.