Breast Cancer Racial Disparities: Unanswered Questions
Breast Cancer Racial Disparities: Unanswered Questions
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DOI：
10.1158/0008-5472.can-10-3021
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发表时间：
2011-02-01
期刊：
影响因子：
11.2
通讯作者：
Underwood, Willie, III
中科院分区：
文献类型：
--
作者：
Ademuyiwa, Foluso O.;Edge, Stephen B.;Underwood, Willie, III
乳腺癌是美国女性中最常见的非皮肤癌，仅次于肺癌，是癌症相关死亡的主要原因。尽管由于各种因素，包括治疗方式和筛查的改善，死亡率一直在稳步下降，但黑人和白人之间的结果仍存在重大种族差异。虽然在卫生保健利用和访问，肿瘤生物学和癌症管理的差异已被阐明为差异的可能原因，它很可能是其他相互作用的存在。因此，本综述的目的是全面概述乳腺癌预后种族差异的文献，并强调可能导致黑人和白人乳腺癌患者之间差异的潜在致病因素。此外，我们通过讨论一些剩余的知识差距提出研究建议，这些知识差距可能会导致进一步了解差异，从而改善所有乳腺癌女性的预后。Cancer Res; 71（3）; 640-4.（C）2010年AACR。
Breast cancer is the most common noncutaneous cancer diagnosed in women in the United States and is second only to lung cancer as the leading cause of cancer-related mortality. Although mortality rates have been dropping steadily due to a variety of factors including improved treatment modalities and screening, substantial racial differences in outcome between blacks and whites persist. Although differences in health care utilization and access, tumor biology, and cancer management have been elucidated as possible reasons for disparities seen, it is likely that other interactions exist. The purpose of this review is, therefore, to present a comprehensive overview of the literature on racial disparities in breast cancer outcome and highlight potential causative factors that may contribute to disparities seen among blacks and whites with breast cancer. In addition, we make research recommendations by discussing some of the remaining gaps in knowledge that may lead to further understanding of disparities and consequently improved outcomes for all women with breast cancer. Cancer Res; 71(3); 640-4. (C)2010 AACR.