Retinal Vascular Changes are a Marker for Cerebral Vascular Diseases.
Retinal Vascular Changes are a Marker for Cerebral Vascular Diseases.
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DOI：
10.1007/s11910-015-0561-1
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发表时间：
2015-07
影响因子：
5.6
通讯作者：
Moss HE
中科院分区：
文献类型：
--
作者：
Moss HE
视网膜循环是脑血管疾病的潜在标志，因为它与颅内循环共享起源和引流，并且因为它可以使用检眼镜直接可视化。横断面和队列研究已经证明了慢性视网膜和脑血管疾病、急性视网膜和脑血管疾病以及慢性视网膜血管疾病和急性脑血管疾病之间的相关性。特别是，视网膜病变、视网膜动脉阻塞和视网膜静脉口径增加的某些定性特征与并发和未来的脑血管事件相关。在考虑了已知在两种循环中引起疾病的混杂变量后，这些相关性仍然存在，这支持了视网膜血管系统结果在脑血管疾病风险方面对个体进行分层的潜在用途。
The retinal circulation is a potential marker of cerebral vascular disease because it shares origin and drainage with the intracranial circulation and because it can be directly visualized using ophthalmoscopy. Cross sectional and cohort studies have demonstrated associations between chronic retinal and cerebral vascular disease, acute retinal and cerebral vascular disease and chronic retinal vascular disease and acute cerebral vascular disease. In particular, certain qualitative features of retinopathy, retinal artery occlusion and increased retinal vein caliber are associated with concurrent and future cerebrovascular events. These associations persist after accounting for confounding variables known to be disease-causing in both circulations, which supports the potential use of retinal vasculature findings to stratify individuals with regards to cerebral vascular disease risk.