Type 2 and other forms of diabetes in 0-30 year olds: a hospital based study in Leeds, UK

Type 2 and other forms of diabetes in 0-30 year olds: a hospital based study in Leeds, UK
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DOI:
10.1136/adc.88.8.676
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发表时间:
2003-08-01
影响因子:
5.2
通讯作者:
Bodansky, HJ
Bodansky, HJ
中科院分区:
医学2区
文献类型:
--
作者:
Feltbower, RG;McKinney, PA;Bodansky, HJ

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背景和目标:根据最近关于越来越多的青少年被诊断为成人或2型糖尿病的报道,我们旨在描述英格兰北方城市儿童和年轻人中2型和其他类型糖尿病的患病率。方法:在利兹的糖尿病门诊中,对年龄小于或等于30岁的患者进行了一项基于医院的横断面研究2000.Results:共确定了677例受试者,其中621例(92%)和37例(5%)分别患有1型和2型糖尿病。四名患者已证实的成熟发病糖尿病的年轻人,而原因是不确定的四个。所有患者的中位年龄为22岁,396例(58%)年龄为20 - 30岁; 37例2型糖尿病患者中有32例年龄为20 - 30岁。2型糖尿病的患病率为0.13/1000,而1型糖尿病患者为2.2/1000。在所有2型糖尿病患者中,24%为南亚人,而背景人群为5%; 87%被归类为汤森评分的两个最不富裕的三分位数。这种联系与剥夺是没有解释的亚洲患者的比例跨三分位数(约25%)。结论:这项研究表明,2型糖尿病的患病率极低,在10 - 19奥尔兹的青少年,但将提供一个基线为未来的比较。总的来说,2型糖尿病在南亚人中更常见,并与剥夺有关。
Background and Aims: Following recent reports of increased numbers of adolescents being diagnosed with the adult or type 2 form of diabetes we aimed to describe the prevalence of both type 2 and other forms of diabetes in an urban population of children and young people in northern England.Methods: A hospital based cross sectional study was performed in patients aged less than or equal to 30 years attending diabetic clinics in Leeds during the year 2000.Results: A total of 677 subjects were identified, of whom 621 ( 92%) and 37 ( 5%) had type 1 and type 2 diabetes respectively. Four patients had confirmed maturity onset diabetes of the young, while the cause was uncertain for four. Median age of all patients was 22 years, with 396 (58%) aged 20 - 30; 32/37 patients with type 2 diabetes were aged 20 - 30. The prevalence of type 2 diabetes was 0.13 per 1000 overall, compared to 2.2 per 1000 for patients with type 1 diabetes. Of all type 2 diabetes patients, 24% were south Asian compared to 5% of the background population; 87% were categorised into the two least affluent tertiles of the Townsend score. This link with deprivation was not explained by the proportion of Asian patients across tertiles ( approximately 25%).Conclusions: This study shows extremely low prevalence of type 2 diabetes in 10 - 19 year olds, but will provide a baseline for future comparisons. Overall, type 2 diabetes is seen more commonly in south Asians, and an association with deprivation is suggested.