Living-donor liver transplantation in adults: Tokyo University experience.
Living-donor liver transplantation in adults: Tokyo University experience.
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成人活体肝移植：东京大学的经验。
DOI：
10.1007/s10534-002-0735-6
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
N. Kokudo
中科院分区：
文献类型：
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作者：
Y. Sugawara;M. Makuuchi;J. Kaneko;T. Ohkubo;Y. Matsui;H. Imamura;N. Kokudo
本研究的目的是分析单中心成人患者活体肝移植（LDLT）的经验。分析了90例连续LDLT手术。检查术前状态、发病率、住院时间、术后移植物功能和存活率。供体仅表现出极低的发病率，并在LDLT后15 ± 6天出院。患者的并发症包括急性排斥反应（32%）、血管并发症（8%）和胆道并发症（20%）。死亡率为6%，另有3例患者发生晚期死亡。2年累积生存率为92%。目前的结果表明，LDLT可以在成人患者中进行，并具有可接受的结局。
The objective of this study was to analyze the experience of a single center with living‐donor liver transplantation (LDLT) for adult patients. Ninety consecutive LDLT procedures were analyzed. Preoperative status, morbidity, hospital stay duration, and postoperative graft function and survival rates were examined. Donors showed only minimal morbidity and were discharged 15 ± 6 days after LDLT. Morbidity in the patients included acute rejection (32%), vascular complications (8%), and biliary complications (20%). The mortality rate was 6% and three additional patients experienced late death. The 2‐year cumulative survival rate was 92%. The present results suggest that LDLT can be performed with an acceptable outcome in adult patients.