Estimating diagnostic accuracy without a gold standard: A continued controversy
Estimating diagnostic accuracy without a gold standard: A continued controversy
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DOI：
10.1080/10543406.2016.1226334
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发表时间：
2016-01-01
影响因子：
1.1
通讯作者：
Albert, Paul S.
中科院分区：
文献类型：
--
作者：
Collins, John;Albert, Paul S.
在生物统计学和流行病学文献中有大量关于估计诊断准确性的文献，例如二元测试的敏感性和特异性，而没有金标准。这种方法非常有吸引力，因为在某些情况下获得黄金标准信息是不可能的、困难的，或者非常昂贵的。尽管这些方法有许多支持者，但也有一些严重的批评。我们回顾了重要的方法发展，并讨论了方法的问题。我们提出了可能较少争议的替代设计，并为未来的研究提出了想法。最后，我们就如何在实践中使用这些方法提出了建议。
There is a wide body of literature in biostatistics and epidemiology literature about estimating diagnostic accuracy, such as sensitivity and specificity of a binary test, without a gold standard. This methodology is very attractive since obtaining gold standard information is impossible, difficult, or very expensive in some situations. Although there are many proponents of these approaches, there have also been some serious criticisms. We review important methodological developments as well as discuss problems with the approaches. We propose alternative designs that may be less controversial and present ideas for future research. Lastly, we provide recommendations about how these methods should be used in practice.