Health-related quality of life in women with fibromyalgia: clinical and psychological factors associated
Health-related quality of life in women with fibromyalgia: clinical and psychological factors associated
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DOI：
10.1007/s10067-011-1870-7
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发表时间：
2012-02-01
影响因子：
3.4
通讯作者：
Rodriguez Vazquez, Maria Isabel
中科院分区：
文献类型：
--
作者：
Campos, Ricardo Pereira;Rodriguez Vazquez, Maria Isabel
该研究的目的是分析纤维肌痛（FM）对健康相关生活质量（HRQOL）的影响，并确定与疾病相关的临床和心理因素。一项横断面研究进行了与FM的成年葡萄牙妇女。分析数据包括人口统计学、临床和心理变量以及HRQOL：SF-36和纤维肌痛影响问卷（FIQ）。HRQOL与其他变量之间的关系采用双变量分析。为了评估临床和心理变量的相对贡献，设计并进行了一系列多元回归分析。研究样本包括76名FM女性（49.61 +/- 10.07岁）。FM对HRQOL的各个维度都有影响，尤其是身体功能、身体角色功能和总体健康。平均FIQ总分为68.59 +/- 17.54，40例患者（53%）的得分为千分之一70。通过10 cm视觉模拟量表（VAS）评估的疼痛强度是HRQOL的重要预测因子，与FIQ和SF-36的所有维度（情感角色功能除外）相关。焦虑（医院焦虑抑郁量表（HADS））是心理健康和一般健康状况（SF-36）的重要预测因子。抑郁与活力、心理健康、FIQ有关。关注应对与一般健康和情绪角色功能有关，社会支持（社会支持满意度量表）与社会功能有关。这些临床和心理变量解释了可接受的变异比例（R（2）），范围从情感角色功能的31.3%到FIQ的70.6%，除了身体角色功能（R（2）= 6.1）。FM对HRQOL的一般和具体维度都有负面影响，尤其是身体维度。疼痛强度、焦虑和抑郁症状以及以情绪为中心的应对方式是FM对HRQOL影响的最相关解释变量。
The objective of the study was to analyse the impact of fibromyalgia (FM) on health-related quality of life (HRQOL) and to identify clinical and psychological factors associated with the disease. A cross-sectional study was conducted with adult Portuguese women with FM. Analysed data were demographic, clinical and psychological variables and HRQOL: SF-36 and Fibromyalgia Impact Questionnaire (FIQ). The relationship between HRQOL and the other variables was made with a bivariate analysis. To assess the relative contribution of clinical and psychological variables, a series of multiple regression analyses were designed and made. The study sample consisted of 76 women with FM (49.61 +/- 10.07 years). All dimensions of HRQOL were affected in FM, especially Physical Functioning, Physical Role Functioning and General Health. The mean FIQ total score was 68.59 +/- 17.54, and 40 patients (53%) presented scores a parts per thousand yen70. Pain intensity, assessed by a 10-cm visual analogue scale (VAS), was a significant predictor of HRQOL in expressing association with FIQ and all dimensions of SF-36, except Emotional Role Functioning. Anxiety (Hospital Anxiety and Depression Scale (HADS)) was a significant predictor of the Mental Component and General Health (SF-36). Depression (HADS) was related with Vitality, Mental Health and FIQ. Emotion-focused coping was related with General Health and Emotional Role Functioning, and social support (Satisfaction with Social Support Scale (ESSS)) was related with the Social Functioning. These clinical and psychological variables explained an acceptable proportion of variability (R (2)), ranging from 31.3% on Emotional Role Functioning to 70.6% on FIQ, except for Physical Role Functioning (R (2) = 6.1). FM has a negative impact on both general and specific dimensions of HRQOL, especially the physical dimensions. Pain intensity, anxiety and depression symptoms and the emotion-focused coping are the most relevant explanatory variables of the impact of FM on HRQOL.