Clinical impact of mild carbohydrate intolerance in pregnancy: A study of 2904 nondiabetic Danish women with risk factors for gestational diabetes mellitus
Clinical impact of mild carbohydrate intolerance in pregnancy: A study of 2904 nondiabetic Danish women with risk factors for gestational diabetes mellitus
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DOI：
10.1067/mob.2001.115864
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发表时间：
2001-08-01
影响因子：
9.8
通讯作者：
Beck-Nielsen, H
中科院分区：
文献类型：
--
作者：
Jensen, DM;Damm, P;Beck-Nielsen, H
目的：目的是研究轻度碳水化合物不耐受在妊娠期糖尿病的危险因素孕妇的临床影响。研究设计：这是一个历史队列研究的2904孕妇检查妊娠期糖尿病的基础上的危险因素。口服葡萄糖耐量试验结果和临床结局的信息收集从实验室图表和医疗records.RESULTS：以下结果增加了显着增加葡萄糖值在口服葡萄糖耐量试验：肩难产，巨大儿，紧急剖宫产，助产，高血压，引产。然而，当校正其他危险因素，高血压和引产仅轻微相关的葡萄糖levels.CONCLUSION：在一组非糖尿病孕妇妊娠糖尿病的危险因素，肩难产和其他母胎并发症的频率有一个分级增加，增加葡萄糖水平在口服葡萄糖耐量试验。
OBJECTIVE: The objective was to study the clinical impact of mild carbohydrate intolerance In pregnant women with risk factors for gestational diabetes mellitus.STUDY DESIGN: This was a historical cohort study of 2904 pregnant women examined for gestational diabetes on the basis of risk factors. Information on oral glucose tolerance test results and clinical outcomes was collected from laboratory charts and medical records.RESULTS: The following outcomes Increased significantly with increasing glucose values during the oral glucose tolerance test: shoulder dystocia, macrosomia, emergency cesarean section, assisted delivery, hypertension, and Induction of labor. However, when corrections were made for other risk factors, hypertension and induction of labor were only marginally associated with glucose levels.CONCLUSION: In a group of nondiabetic pregnant women with risk factors for gestational diabetes, there was a graded increase in the frequency of shoulder dystocia and other maternal-fetal complications with Increasing glucose levels during an oral glucose tolerance test.