In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching
In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching
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DOI：
10.1016/j.jmbbm.2016.05.035
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发表时间：
2016-09-01
影响因子：
3.9
通讯作者：
Carre, Matthew J.
中科院分区：
文献类型：
--
作者：
Maiti, Raman;Gerhardt, Lutz-Christian;Carre, Matthew J.
角质层和表皮层的厚度和粗糙度随性别、年龄和解剖部位而变化。需要与这些结构变化相关的皮肤的机械和摩擦学特性的知识，以帮助设计外骨骼、假体、矫形器、用于运动学测量的身体安装传感器以及最佳使用可穿戴的身体上设备。在这个案例研究中，光学相干断层扫描（OCT）和数字图像相关（DIC）相结合，以确定皮肤表面应变和亚表面变形行为的掌侧前臂由于自然组织拉伸。在臂角从屈曲（90）到完全伸展（180）的变化过程中，计算表皮厚度以及真皮-表皮交界边界的几何变化。这种姿势变化通常会导致皮肤表面拉格朗日应变增加。25%，这在上皮肤层中引起相当大的形态学变化，这通过表皮层厚度的减小（20%）、真皮-表皮接合部起伏的平坦化（平坦度的45-50%减小，表示为Ra和Rz粗糙度轮廓高度变化）和皮肤表面粗糙度Ra和Rz的减小（40-50%）来证明。新开发的方法，DIC结合OCT成像，是一种强大的，快速的和非侵入性的方法来研究结构的皮肤变化，在真实的时间和组织反应引起的机械负荷或拉伸。(C)2016年6月，作者。爱思唯尔有限公司出版
Stratum corneum and epidermal layers change in terms of thickness and roughness with gender, age and anatomical site. Knowledge of the mechanical and tribological properties of skin associated with these structural changes are needed to aid in the design of exoskeletons, prostheses, orthotics, body mounted sensors used for kinematics measurements and in optimum use of wearable on-body devices. In this case study, optical coherence tomography (OCT) and digital image correlation (DIC) were combined to determine skin surface strain and sub-surface deformation behaviour of the volar forearm due to natural tissue stretching. The thickness of the epidermis together with geometry changes of the dermal-epidermal junction boundary were calculated during change in the arm angle, from flexion (90) to full extension (180). This posture change caused an increase in skin surface Lagrange strain, typically. by 25% which induced considerable morphological changes in the upper skin layers evidenced by reduction of epidermal layer thickness (20%), flattening of the dermal-epidermal junction undulation (45-50% reduction of flatness being expressed as Ra and Rz roughness profile height change) and reduction of skin surface roughness Ra and Rz (40-50%). The newly developed method, DIC combined with OCT, imaging, is a powerful, fast and non-invasive methodology to study structural skin changes in real time and the tissue response provoked by mechanical loading or stretching. (C) 2016 The Authors. Published by Elsevier Ltd.