Collagen/hydroxyapatite composite materials with desired ceramic properties

Collagen/hydroxyapatite composite materials with desired ceramic properties
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DOI:
10.1093/jmicro/dfr010
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发表时间:
2011-06-01
期刊:
JOURNAL OF ELECTRON MICROSCOPY
影响因子:
--
通讯作者:
Ficai, Anton
Ficai, Anton
中科院分区:
其他
文献类型:
--
作者:
Andronescu, Ecaterina;Voicu, Georgeta;Ficai, Anton

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我们的目的是获得和表征一些胶原/羟基磷灰石(科尔/HA)杂化复合材料与所需的陶瓷性能。这些材料的陶瓷特性是通过结合两种干燥方法实现的:在30摄氏度下控制空气干燥,然后冷冻干燥。通过空气干燥时间的作用,材料形态从多孔材料(当材料被冷冻干燥时)变化到致密材料(当材料被空气干燥时),而组合干燥允许我们获得中间形态。采用XRD、FTIR、SEM等方法对复合材料进行了表征,并采用亚瑟法测定了复合材料的陶瓷性能。这些科尔/HA复合材料的陶瓷性能在大范围内变化,例如材料的密度从0.06到1.5g/cm(3)变化,而孔隙率从96.5%到27.5%变化。
Our purpose was to obtain and characterize some collagen/hydroxyapatite (COLL/HA) hybrid composite materials with desired ceramic properties. The ceramic properties of these materials were achieved by combining two drying methods: controlled air drying at 30 degrees C followed by freeze-drying. Through the function of the air drying times, the materials morphology varies from porous materials (when the materials are freeze-dried) up to dense materials (when the materials are air-dried), while the combined drying allows us to obtain an intermediary morphology. The composite materials intended to be used as bone grafts and in a drug delivery system were characterized by XRD, FTIR, SEM, and also by determining the ceramic properties by using the Arthur method. The ceramic properties of these COLL/HA composite materials vary in large range, for instance the density of the materials varies from 0.06 up to 1.5 g/cm(3) while the porosity varies from 96.5% down to 27.5%.