Investigating the neural basis of basic human movement perception using multi-voxel pattern analysis
Investigating the neural basis of basic human movement perception using multi-voxel pattern analysis
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DOI：
10.1007/s00221-018-5175-9
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发表时间：
2018-01
影响因子：
2
通讯作者：
Fangyuan Ma;Junhai Xu;Xianglin Li;Pei-yuan Wang;Bin Wang;Baolin Liu
中科院分区：
文献类型：
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作者：
Fangyuan Ma;Junhai Xu;Xianglin Li;Pei-yuan Wang;Bin Wang;Baolin Liu
人类可以熟练地从他人的身体动作中识别动作，并立即做出判断或反应。以往的神经影像学研究大多利用减少和短暂的人类运动刺激，并指出人类枕颞叶皮层在生物运动识别中起着关键作用。目前还不清楚在多大程度上，与人类运动感知相关的区域参与解码基本运动。由于人体的运动自然来源于人体姿势的序列，所以我们采用了真实的运动刺激。在一个封闭的功能磁共振成像实验中，参与者被展示了四种人类运动（跳跃，跑步，跳跃和步行）。采用多体素模式分析（MVPA）来评估是否可以区分不同的运动在四个区域。我们发现，运动特异性信息在人体敏感区，外纹体区（EBA）和运动敏感区，后上级颞沟（pSTS）和人类中颞复合体（hMT+）。此外，以EBA为种子进行了进一步的功能连接分析，结果表明EBA与参与行为感知和运动控制的多个区域存在任务调制的功能连接。人体运动处理似乎是在分布式网络中完成的。枕颞叶皮层可以完成人体运动信息提取的初步处理，然后将其转换到相互连接的区域以供进一步利用。
Humans can skillfully recognize actions from others’ body motion and make a judgment or response at once. Previous neuroimaging studies have mostly utilized diminished and brief human motion stimuli and indicated that human occipito-temporal cortex plays a critical role at biological motion recognition. It remains unclear to what extent that the areas related to human motion perception are involved in decoding basic movements. Because human movement naturally stems from the sequences of body posture, so we utilized the stimulus of real movements. Participants were presented four categories of human movements (jump, run, skip and walk) in a blocked fMRI experiment. Multi-voxel pattern analysis (MVPA) was adopted to assess whether different movements could be discriminated in four regions. We found that movement-specific information was represented in both human body-sensitive areas, extrastriate body area (EBA) and motion-sensitive areas, posterior superior temporal sulcus (pSTS) and human middle temporal complex (hMT+). Additionally, a further functional connectivity analysis using EBA as a seed was conducted and it suggested that EBA showed a task-modulated functional connectivity with multiple areas that were involved in the behavior perception and motor control. Human motion processing appeared to be completed in a distributed network. The occipito-temporal cortex may perform the initial processing of human motion information extracting, and then transform them to interconnected areas for a further utilization.