Protein dynamics: comparison of simulations with inelastic neutron scattering experiments
Protein dynamics: comparison of simulations with inelastic neutron scattering experiments
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DOI：
10.1017/s0033583500003723
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发表时间：
1991-08
影响因子：
6.1
通讯作者：
Jeremy C. Smith
中科院分区：
文献类型：
--
作者：
Jeremy C. Smith
为了加深我们对决定球状蛋白质折叠和功能的原理的理解，在确定其三维结构的同时，还必须对它们的内部运动进行表征。虽然蛋白质中的动力学事件发生在从飞秒到至少秒的时间尺度上，但球状蛋白质的物理性质是皮秒（ps）时间尺度的运动对原子从其平均位置的内部波动做出了特别重要的贡献。
To deepen our understanding of the principles determining the folding and functioning of globular proteins the determination of their three-dimensional structures must be supplemented with the characterization of their internal motions. Although dynamical events in proteins occur on time-scale ranging from femtoseconds to at least seconds, the physical properties of globular proteins are such that picosecond (ps) time-scale motions make a particularly important contribution to the internal fluctuations of the atoms from their mean positions.