DERIVATIVE CHROMOSOMAL STRUCTURES FROM A RING CHROMOSOME-4
DERIVATIVE CHROMOSOMAL STRUCTURES FROM A RING CHROMOSOME-4
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DOI：
10.1007/bf00272478
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发表时间：
1975-01-01
期刊：
影响因子：
--
通讯作者：
PASSARGE, E
中科院分区：
文献类型：
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作者：
NISS, R;PASSARGE, E
本报告描述了对4号环状染色体个体的中期、后期和间期培养淋巴细胞的研究结果。90.1%的中期存在环。特别关注了衍生染色体结构的发生，如部分复制和三复制环、三心环、3个互锁环链、棒状染色体、“粉状”环等。个体的临床特征（身材矮小，智力发育受损，拇指发育不全，上睑下垂，男性外生殖器发育不全，皮肤纹模式异常）不符合特定表型。
This report describes the results from cultured lymphocytes studied at metaphase, anaphase, and interphase from an individual with a ring chromosome 4. A ring was present in 90.1% of metaphases. Special attention was directed towards the occurrence of derivative chromosomal structures, such as partially duplicated and triplicated rings, tricentric rings, chains of 3 interlocked rings, rod-shaped chromosomes, “pulverized” rings, and others.The clinical features of the individual (small stature and impaired mental development, hypoplastic thumbs, ptosis palpebrae hypoplastic external male genitalia, abnormal dermatoglyphic pattern) did not conform to a specific phenotype.