Spontaneous pneumomediastinum, pneumothorax and subcutaneous emphysema in COVID-19 pneumonia: a rare case and literature review.
Spontaneous pneumomediastinum, pneumothorax and subcutaneous emphysema in COVID-19 pneumonia: a rare case and literature review.
复制标题
DOI：
10.1136/bcr-2020-239489
复制
发表时间：
2020-12-12
期刊：
影响因子：
0.9
通讯作者：
Rodriguez-Fuentes Y
中科院分区：
文献类型：
--
作者：
Elhakim TS;Abdul HS;Pelaez Romero C;Rodriguez-Fuentes Y
最近有报道称，与正压通气无关的自发性肺气肿（SPM）和气胸（PNX）是严重COVID-19肺炎病例中的一种罕见并发症。推测其病理生理机制是弥漫性肺泡损伤导致肺泡破裂和漏气。我们介绍了一例入院后第13天并发SPM、PNX和皮下肺气肿的COVID-19肺炎病例，该患者没有可识别的此类并发症风险因素。患者接受了COVID-19感染的药物治疗，未使用侵入性或非侵入性呼吸机。此外，他不吸烟，无肺部合并症，从未报告咳嗽。他最终出院回家，情况稳定。一项全面的文献综述显示，15例COVID-19肺炎患者发生SPM。
Spontaneous pneumomediastinum (SPM) and pneumothorax (PNX) unrelated to positive pressure ventilation has been recently reported as an unusual complication in cases of severe COVID-19 pneumonia. The presumed pathophysiological mechanism is diffuse alveolar injury leading to alveolar rupture and air leak. We present a case of COVID-19 pneumonia complicated on day 13 post admission by SPM, PNX and subcutaneous emphysema in a patient with no identifiable risk factors for such complication. The patient received medical treatment for his COVID-19 infection without the use of an invasive or non-invasive ventilator. Moreover, he is a non-smoker with no lung comorbidities and never reported a cough. He was eventually discharged home in stable condition. A comprehensive literature review revealed 15 cases of SPM developing in patients with COVID-19 pneumonia.