Diabetes and Risk of Hearing Impairment in Adults: A Meta-Analysis
Diabetes and Risk of Hearing Impairment in Adults: A Meta-Analysis
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DOI：
10.1210/jc.2012-2119
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发表时间：
2013-01-01
影响因子：
5.8
通讯作者：
Sone, Hirohito
中科院分区：
文献类型：
--
作者：
Horikawa, Chika;Kodama, Satoru;Sone, Hirohito
背景：最近，几项研究调查了糖尿病和听力障碍之间的关系，但结果不一致。目的：我们的目的是比较糖尿病和非糖尿病成人之间听力障碍的患病率。数据来源：我们使用 MEDLINE（1950 年至 2011 年 5 月 30 日）和 EMBASE（1974 年至 2011 年 5 月 30 日）进行了系统的文献检索。研究选择：如果提供了听力受损和非听力受损糖尿病病例数的数据，则纳入横断面研究。听力障碍仅限于通过纯音测听法评估的听力障碍，包括至少2 kHz的频率范围，并被定义为进行性、慢性、感音神经性或无特定原因。 数据提取：两位作者独立提取相关数据。将每项研究中计算的与糖尿病相关的听力障碍的比值比 (OR) 与随机效应模型进行汇总。数据综合：数据来自 13 项符合条件的研究（20,194 名受试者和 7,377 例病例）。与非糖尿病参与者相比，糖尿病参与者听力障碍的总体汇总 OR（95% 置信区间）为 2.15 (1.72-2.68)。年轻参与者的 OR 较高（平均年龄、
Context: Recently, several studies have investigated the relationship between diabetes and hearing impairment, but results were inconsistent.Objective: Our objective was to compare the prevalence of hearing impairment between diabetic and nondiabetic adults. Data Sources : We performed a systematic literature search using MEDLINE (1950 to May 30, 2011) and EMBASE (1974 to May 30, 2011).Study Selection: Cross-sectional studies were included if data on numbers of hearing-impaired and non-hearing-impaired cases with diabetes were presented. Hearing impairment was limited to that assessed by pure-tone audiometry that included at least 2 kHz of frequency range and was defined as progressive, chronic, sensorineural, or without specified cause.Data Extraction: Two authors independently extracted relevant data. Odd ratios (ORs) of hearing impairment related to diabetes calculated in each study were pooled with the random-effects model.Data Synthesis: Data were obtained from 13 eligible studies (20,194 participants and 7,377 cases). Overall pooled OR (95% confidence interval) of hearing impairment for diabetic participants compared with nondiabetic participants was 2.15 (1.72-2.68). OR was higher in younger participants (mean age,