DIRECT CORTICAL REPRESENTATION OF DRAWING
DIRECT CORTICAL REPRESENTATION OF DRAWING
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DOI：
10.1126/science.8036499
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发表时间：
1994-07-22
期刊：
影响因子：
56.9
通讯作者：
SCHWARTZ, AB
中科院分区：
文献类型：
--
作者：
SCHWARTZ, AB
行动意图如何导致运动是大脑组织的一个基本问题。最近的工作表明，这种操作涉及大量神经元群体的协作相互作用。通过将神经元活动转换到空间域，使用群体向量方法来可视化恒河猴绘制螺旋时手部轨迹的运动皮层表示。在整个任务中计算的一系列总体向量准确地反映了手部路径。在这种皮质表征中发现了将速度与曲率相关的心理物理学规则，即“幂律”。每个种群向量和相应移动部分之间的相对时间是可变的。人口矢量仅在曲率半径大于 6 厘米的螺旋部分中以预测方式先于移动。这些结果表明，运动轨迹是运动皮层活动的重要决定因素，并且运动皮层活动的这一方面可能仅对绘画运动的离散部分有贡献。
How the intention to act results in movement is a fundamental question of brain organization. Recent work has shown that this operation involves the cooperative interaction of large neuronal populations. A population vector method, by transforming neuronal activity to the spatial domain, was used to visualize the motor cortical representation of the hand's trajectory made by rhesus monkeys as they drew spirals. Hand path was accurately reflected by a series of population vectors calculated throughout the task. A psychophysical rule relating speed to curvature, the ''power law,'' was found in this cortical representation. The relative timing between each population vector and the corresponding portion of the movement was variable. The population vectors only preceded the movement in a predictive manner in portions of the spiral where the radius of curvature was greater than 6 centimeters. These results show that the movement trajectory is an important determinant of motor cortical activity and that this aspect of motor cortical activity may contribute only to discrete portions of the drawing movement.