The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength
The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength
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DOI：
10.1016/j.metabol.2004.07.012
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发表时间：
2005-02-01
影响因子：
9.8
通讯作者：
Aagaard, P
中科院分区：
文献类型：
--
作者：
Andersen, LL;Tufekovic, G;Aagaard, P
急性肌肉蛋白质代谢不仅受到抗阻运动的调节，而且受到氨基酸的调节。然而，很少有人知道蛋白质补充与阻力训练相结合的长期肥大效应。本研究旨在比较14周的阻力训练结合定时摄入等能蛋白质与碳水化合物补充对肌纤维肥大和机械肌肉性能的影响。在每次训练前和训练后立即补充，此外，在非训练日的早晨补充。从股外侧肌获得肌肉活检标本，并分析肌纤维横截面积。在测力台上进行蹲跳和反向运动跳，测定纵跳高度。在等速测力计上测量膝伸肌慢速（30 ° s（-1））和快速（240 ° s（-1））同心和离心收缩时的峰值扭矩。经过14周的阻力训练后，蛋白质组显示I型肌纤维（18% +/- 5%; P < .01）和II型肌纤维（26% +/- 5%; P < .01）肥大，而碳水化合物组没有发生高于基线的变化。蹲跳高度仅在蛋白质组增加，而反向运动跳跃高度和峰值扭矩在缓慢等速肌肉收缩增加相似的两组。总之，在阻力训练中补充蛋白质比补充碳水化合物对机械肌肉功能有一个小的优势，但是，目前的结果可能与那些对增加肌肉尺寸特别感兴趣的人有关。(C)2005年爱思唯尔公司All rights reserved.
Acute muscle protein metabolism is modulated not only by resistance exercise but also by amino acids. However, less is known about the long-term hypertrophic effect of protein supplementation in combination with resistance training. The present study was designed to compare the effect of 14 weeks of resistance training combined with timed ingestion of isoenergetic protein vs carbohydrate supplementation on muscle fiber hypertrophy and mechanical muscle performance. Supplementation was administered before and immediately after each training bout and, in addition, in the morning on nontraining days. Muscle biopsy specimens were obtained from the vastus lateralis muscle and analyzed for muscle fiber cross-sectional area. Squat jump and countermovement jump were performed on a force platform to deterinine vertical jump height. Peak torque during slow (30degrees s(-1)) and fast (240degrees s(-1)) concentric and eccentric contractions of the knee extensor muscle was measured in an isokinetic dynamometer. After 14 weeks of resistance training, the protein group showed hypertrophy of type I (18% +/- 5%; P < .01) and type II (26% +/- 5%; P < .01) muscle fibers, whereas no change above baseline occurred in the carbohydrate group. Squat jump height increased only in the protein group, whereas countermovement jump height and peak torque during slow isokinetic muscle contraction increased similarly in both groups. In conclusion, a minor advantage of protein supplementation over carbohydrate supplementation during resistance training on mechanical muscle function was found. However, the present results may have relevance for individuals who are particularly interested in gaining muscle size. (C) 2005 Elsevier Inc. All rights reserved.