Characterization of superparamagnetic Fe3O4 nanoparticles by fluxgate magnetorelaxometry for use in biomedical applications
Characterization of superparamagnetic Fe3O4 nanoparticles by fluxgate magnetorelaxometry for use in biomedical applications
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DOI：
10.1063/1.2840048
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发表时间：
2008-04-01
影响因子：
3.2
通讯作者：
Enpuku, K.
中科院分区：
文献类型：
--
作者：
Ludwig, F.;Heim, E.;Enpuku, K.
我们利用差动磁通门装置研究了不同Fe3O4纳米颗粒悬浮液的磁驰豫测量(MRX)。为了估算有机壳层磁性纳米颗粒(MNPs)的流体力学尺寸分布，采用团簇力矩叠加模型。对同一批MNPs在不同粘度的水-甘油混合物中稀释的一系列样品的实验表明，该模型适用于MNPs和团簇的流体力学尺寸分布的估计。由于MRX测量只持续几秒钟，因此它也非常适合于研究聚集动力学。这一点在硅壳悬浮在5%磷酸盐缓冲盐水中的MNPs上得到了证明。(C)2008年美国物理研究所。
We have investigated the magnetorelaxometry (MRX) of various Fe3O4 nanoparticle suspensions utilizing a differential fluxgate setup. To estimate the distribution of the hydrodynamic size of the magnetic nanoparticles (MNPs) with organic shell, the cluster moment superposition model is applied. On a sample series of MNPs from the same batch diluted in water-glycerine mixtures of varying viscosity, it is demonstrated that the model is suited for the estimation of the distribution of the hydrodynamic size of MNPs and clusters. Since a MRX measurement lasts only a few seconds, it is also highly suited to study the aggregation kinetics. This is demonstrated on MNPs with silica shell suspended in 5% phosphate-buffered saline solution. (c) 2008 American Institute of Physics.