Multiphoton-excited serotonin photochemistry
Multiphoton-excited serotonin photochemistry
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DOI：
10.1016/s0006-3495(04)74370-2
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发表时间：
2004-05-01
影响因子：
3.4
通讯作者：
Shear, JB
中科院分区：
文献类型：
--
作者：
Gostkowski, ML;Allen, R;Shear, JB
我们报告了对血清素多光子激发反应的光化学和光物理研究，该反应先前已被证明可以产生能够在可见光谱区域广泛发射的光产物。目前的研究表明，通过三光子吸收制备的中间态对近红外光的吸收提高了光产物的形成产率，在钛：蓝宝石激发源的短波长极限处观察到最大的作用截面（类似于10（-19）cm（2））。该中间状态显示持续至少数十纳秒，并且可能与之前报道的氧敏感中间状态不同。此外，测定了荧光光产物的双光子荧光作用光谱，发现在大约780 nm（3.2 eV）处具有最大值。提出了该光化学过程的一般机制。
We report photochemical and photophysical studies of a multiphoton-excited reaction of serotonin that previously has been shown to generate a photoproduct capable of emitting broadly in the visible spectral region. The current studies demonstrate that absorption of near-infrared light by an intermediate state prepared via three-photon absorption enhances the photoproduct formation yield, with the largest action cross sections (similar to10(-19) cm(2)) observed at the short-wavelength limit of the titanium: sapphire excitation source. The intermediate state is shown to persist for at least tens of nanoseconds and likely to be different from a previously reported oxygen-sensitive intermediate. In addition, the two-photon fluorescence action spectrum for the fluorescent photoproduct was determined and found to have a maximum at similar to780 nm (3.2 eV). A general mechanism for this photochemical process is proposed.