Association of leisure-time physical activity on inflammation markers (C-reactive protein, white cell blood count, serum amyloid A, and fibrinogen,) in healthy subjects (from the ATTICA study)
Association of leisure-time physical activity on inflammation markers (C-reactive protein, white cell blood count, serum amyloid A, and fibrinogen,) in healthy subjects (from the ATTICA study)
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DOI：
10.1016/s0002-9149(02)03175-2
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发表时间：
2003-02-01
影响因子：
2.8
通讯作者：
Toutouzas, PK
中科院分区：
文献类型：
--
作者：
Pitsavos, C;Chrysohoou, C;Toutouzas, PK
整个世纪，心血管疾病的预防和治疗一直是众多研究者关注的焦点。可能影响疾病发生的因素之一是体育活动的有益影响，这在几项研究中已经讨论过。(1-3)此外，最近的研究提供了证据，表明炎症在心血管疾病的发病机制中起作用。（4，5）一些研究人员已经解决了健身和炎症过程之间的关联，（6-9）但这种关系的强度尚未得到充分研究。本研究的目的是评估不同水平的休闲时间体力活动对炎症标志物的影响，如高敏C反应蛋白（CRP），纤维蛋白原，淀粉样蛋白A和白色血细胞（WBC）计数，在一个基于人群的健康成人样本中。
Throughout the 20th century, many researchers focused their interest on prevention and therapy of cardiovascular diseases. Among the factors that may influence the occurrence of disease is the beneficial effect of physical activity, which has been discussed in several studies.(1-3) In addition, recent studies have provided evidence that inflammation plays a role in the pathogenesis of cardiovascular disease.(4,5) Several investigators have addressed the association between fitness and the inflammation process,(6-9) but the strength of this relation has not been fully investigated. The aim of this study is to evaluate the effect of various levels of leisure-time physical activity on inflammation markers,, such as high-sensitivity C-reactive protein (CRP), fibrinogen, amyloid A, and white blood cell (WBC) counts, in a population-based sample of healthy adults.