Induction and analysis of nephrotoxic serum nephritis in mice.
Induction and analysis of nephrotoxic serum nephritis in mice.
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DOI:
10.1007/978-1-4939-0882-0_15
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发表时间:
2014-01-01
期刊:
影响因子:
--
通讯作者:
Vielhauer, Volker
中科院分区:
文献类型:
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作者:
Hoppe, John M;Vielhauer, Volker
The nephrotoxic serum nephritis (NTN) model is an integral part of experimental glomerulonephritis (GN) research. Here, we discuss how the murine NTN model can be induced and effectively used to mimic an immune complex-mediated GN. Further, we differentiate between heterologous and autologous models by comparing pathophysiology and phenotypic manifestations.