STRUCTURES OF MONTANINE, COCCININE, AND MANTHINE
STRUCTURES OF MONTANINE, COCCININE, AND MANTHINE
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DOI：
10.1021/jo01082a019
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发表时间：
1960-01-01
影响因子：
3.6
通讯作者：
WILDMAN, WC
中科院分区：
文献类型：
--
作者：
INUBUSHI, Y;FALES, HM;WILDMAN, WC
蒙丹宁、可可碱和甘氨酸均为石蒜科生物碱，来源于一个新的环系--5，5Li-Me单吗啉。降解性证据和人工证据证实，蒙丹宁、可可碱和甘氨酸分别为XI、XV和X。这组新的生物碱中包含了甘氨酸、CnHiaNCH和Brunsviine的证据。该系列的两篇早期论文4·5描述了从不同种的石蒜科植物鳞茎中分离和鉴定的生物碱。这个属原产于南非。随后的分离研究，主要是在我们的实验室和H.-G.Bolt教授的研究表明，许多海曼藻生物碱丰富地出现在该科的其他属中，这些属很容易获得
Montanine, coccinine, and manthine are shown to be Amaryllidaceae alkaloids derivedfrom a new ring system, 5, li-me thanomorphanthridine. Degradative and synthetic evidence establishes montanine, coccinine, and manthine as XI, XV, and X, respectively. Evidence for the inclusion of manthidine, CnHiaNCh, and brunsvigine in this new group of alkaloids is presented.Two early papers of this series4· 5 described the isolation and characterization of Amaryllidaceae alkaloids from bulbs of various Haemanthus species. This genus is native to South Africa. Subsequent isolation studies, largely in our laboratory and that of Prof. H.-G. Bolt, have shown that many of the Haemanthus alkaloids occur abundantly in other genera of the family which are quite accessible