Air pollution, lung function, and physical symptoms in communities near concentrated Swine feeding operations.
Air pollution, lung function, and physical symptoms in communities near concentrated Swine feeding operations.
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DOI：
10.1097/ede.0b013e3182093c8b
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发表时间：
2011-03
期刊：
影响因子：
--
通讯作者：
Morland KB
中科院分区：
文献类型：
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作者：
Schinasi L;Horton RA;Guidry VT;Wing S;Marshall SW;Morland KB
集中饲养动物会排放可能影响健康的空气污染物。我们研究了居住在养猪场1.5英里范围内的人的身体症状和肺功能与报告的猪气味和监测的空气污染物之间的关系。在2003年9月至2005年9月期间，我们在北卡罗莱纳东部16个社区中分别测量了大约两周的硫化氢（H2S）、内毒素和颗粒物（PM10、PM2.5和PM2.5 - 10）。在同一时间段内，101名成年人每天在屋外坐两次，每次10分钟，报告猪的气味和身体症状，并测量他们的肺功能。使用条件固定效应逻辑回归模型和线性回归模型来得出关联的估计。气味每增加一个单位，室外10分钟后急性眼睛刺激的对数赔率（±1标准误差）增加0.53（±0.06），H2S每增加1 ppb增加0.15（±0.06），PM10每增加10 μg/m3增加0.36（±0.11）。气味和H2S也与前12小时的刺激和呼吸道症状有关。呼吸困难的对数概率每单位气味增加0.50（±0.15）。平均12小时PM2.5浓度每增加10 μg/m3，患者发生喘息的对数概率增加（0.84±0.29），1秒用力呼气量下降（- 0.04±0.02 L）。每增加10 EU/mg内毒素与喉咙痛（0.10±0.05）、胸闷（0.09±0.04）和恶心（0.10±0.05）相关。在一项纵向研究中，在养猪场附近测量的污染物与急性身体症状有关，该研究使用了排除个体时不变特征混淆的分析。
Concentrated animal feeding operations emit air pollutants that may affect health. We examined associations of reported hog odor and of monitored air pollutants with physical symptoms and lung function in people living within 1.5 miles of hog operations. Between September 2003 and September 2005, we measured hydrogen sulfide (H2S), endotoxin, and particulate matter (PM10, PM2.5, and PM2.5–10) for approximately 2-week periods in each of 16 eastern North Carolina communities. During the same time periods, 101 adults sat outside their homes twice a day for 10 minutes, reported hog odor and physical symptoms, and measured their lung function. Conditional fixed-effects logistic and linear regression models were used to derive estimates of associations. The log odds (±1 standard error) of acute eye irritation following 10 minutes outdoors increased by 0.53 (±0.06) for every unit increase in odor, by 0.15 (±0.06) per 1 ppb of H2S, and by 0.36 (±0.11) per 10 μg/m3 of PM10. Odor and H2S were also associated with irritation and respiratory symptoms in the previous 12 hours. The log odds of difficulty breathing increased by 0.50 (±0.15) per unit of odor. A 10 μg/m3 increase in mean 12-hour PM2.5 was associated with increased log odds of wheezing (0.84 ± 0.29) and declines in forced expiratory volume in 1 second (−0.04 ± 0.02 L). A 10 EU/mg increase in endotoxin was associated with increased log odds of sore throat (0.10 ± 0.05), chest tightness (0.09 ± 0.04), and nausea (0.10 ± 0.05). Pollutants measured near hog operations are related to acute physical symptoms in a longitudinal study using analyses that preclude confounding by time-invariant characteristics of individuals.