Influence of personal and family factors on ventilatory function of children.
Influence of personal and family factors on ventilatory function of children.
复制标题
个人及家庭因素对儿童通气功能的影响。
DOI：
10.1136/jech.30.4.219
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
W. Holland
中科院分区：
文献类型：
--
作者：
S. Leeder;R. Corkhill;M. Wysocki;W. Holland
我们想要评估各种个人和家庭因素对幼儿呼吸功能发展的相对影响。在454名儿童中，研究了几个这样的因素与5岁时测量的最大呼气流速之间的关系。这些孩子出生于1963年至1965年之间，出生在伦敦西北部的哈罗，从出生到出生前五年，他们都接受了定期检查。除了与身高的预期关联外，5岁时的最大呼气流率与父母的最大呼气流率的相关性也较小。有下呼吸道疾病病史的儿童的平均峰值流速低于那些逃脱这些疾病的儿童。发病越早、复发越频繁，对呼吸功能的影响越明显。有哮喘和支气管炎病史的儿童的平均最大呼气流速最低，但仅有支气管炎或肺炎病史(即没有哮喘)也与呼吸功能下降有关。在这项研究中，从出生第一年开始的呼吸系统疾病是最有可能改变儿童最大呼气流速的决定因素。
We wanted to assess the relative influence of various personal and family factors upon the development of ventilatory function in young children. The relationship of several such factors to peak expiratory flow rates measured at the age of five years was studied in 454 children. These children were members of a birth cohort born between 1963 and 1965 in Harrow, north-west London, who were examined regularly from birth through the first five years of life. Beside its expected association with height, peak expiratory flow rate at the age of five years was also related to a lesser extent with peak expiratory flow rate in parents. Children with a history of lower respiratory illness had mean peak flow rates which were lower than those of children who escaped these illnesses. The earlier the onset of the illness and the more frequent its recurrence, the more marked its effect on ventilatory function. The group of children with a history of asthma and bronchitis had the lowest mean peak expiratory flow rate, but a history of bronchitis or pneumonia alone (that is, without asthma) was also associated with reduced ventilatory function. Respiratory illness beginning in the first year of life was the most potentially modifiable determinant of peak expiratory flow rate in children in this study.