Prevalence and Risk Factors for Refractive Errors in Indians: The Singapore Indian Eye Study (SINDI)

Prevalence and Risk Factors for Refractive Errors in Indians: The Singapore Indian Eye Study (SINDI)
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DOI:
10.1167/iovs.10-6210
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发表时间:
2011-05-01
影响因子:
4.4
通讯作者:
Saw, Seang-Mei
Saw, Seang-Mei
中科院分区:
医学2区
文献类型:
--
作者:
Pan, Chen-Wei;Wong, Tien-Yin;Saw, Seang-Mei

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目的.确定印度裔新加坡中老年人群屈光不正的患病率和危险因素。对居住在新加坡西南部的40岁以上的印度人进行了一项基于人口的横断面研究。年龄分层(10岁年龄组)随机抽样程序进行选择的参与者。通过自动验光和主观验光确定屈光度。近视定义为等效球镜(SE)< -0.50 D,高度近视定义为SE < -5.00 D,散光定义为柱镜< -0.50 D,远视定义为SE > 0.50 D,屈光参差定义为SE差值> 1.00 D。根据2000年新加坡人口普查对患病率进行了调整。在4497名有资格参加的人中,有3400人(75.6%)接受了检查。完整的数据可用于2805名成年人右眼屈光不正,没有以前的白内障手术。年龄校正的近视患病率为28.0%(95%置信区间[CI],25.8-30.2),高度近视患病率为4.1%(95% CI,3.3-5.0)。近视与年龄增长呈U型关系。年龄校正的散光患病率为54.9%(95% CI,52.0-57.9),远视患病率为35.9%(95% CI,33.7-38.3),屈光参差患病率为9.8%(95% CI,8.61-1.1)。在多元逻辑回归模型中,女性、年轻人、高个子、每天花更多时间阅读和写作或有散光的成年人更容易患近视。年龄较大、近视或糖尿病的成年人有较高的近视风险。在新加坡,印度裔成年人的近视患病率与马来人相似,但低于华人。在新加坡的三个种族群体中,近视的风险因素相似。(Invest Ophthalmol维斯科学。2011;52:3166-3173)DOI:10.1167/iovs.10-6210
PURPOSE. To determine the prevalence and risk factors for refractive errors in middle-aged to elderly Singaporeans of Indian ethnicity.METHODS. A population-based, cross-sectional study of Indians aged over 40 years of age residing in Southwestern Singapore was conducted. An age-stratified (10-year age group) random sampling procedure was performed to select participants. Refraction was determined by autorefraction followed by subjective refraction. Myopia was defined as spherical equivalent (SE) < -0.50 diopters (D), high myopia as SE < -5.00 D, astigmatism as cylinder < -0.50 D, hyperopia as SE > 0.50 D, and anisometropia as SE difference > 1.00 D. Prevalence was adjusted to the 2000 Singapore census.RESULTS. Of the 4497 persons eligible to participate, 3400 (75.6%) were examined. Complete data were available for 2805 adults with right eye refractive error and no prior cataract surgery. The age-adjusted prevalence was 28.0% (95% confidence interval [CI], 25.8-30.2) for myopia and 4.1% (95% CI, 3.3-5.0) for high myopia. There was a U-shaped relationship between myopia and increasing age. The age-adjusted prevalence was 54.9% (95% CI, 52.0-57.9) for astigmatism, 35.9% (95% CI, 33.7-38.3) for hyperopia, and 9.8% (95% CI, 8.61-1.1) for anisometropia. In a multiple logistic regression model, adults who were female, younger, taller, spent more time reading and writing per day, or had astigmatism were more likely to be myopic. Adults who were older or had myopia or diabetes mellitus had higher risk of astigmatism.CONCLUSIONS. In Singapore, the prevalence of myopia in Indian adults is similar to those in Malays, but lower than those in Chinese. Risk factors for myopia are similar across the three ethnic groups in Singapore. (Invest Ophthalmol Vis Sci. 2011;52:3166-3173) DOI:10.1167/iovs.10-6210