Size at birth and its relation to muscle strength in young adult women.
Size at birth and its relation to muscle strength in young adult women.
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DOI：
10.1111/j.1365-2796.2007.01812.x
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发表时间：
2007-09
影响因子：
11.1
通讯作者：
中科院分区：
文献类型：
--
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目的：评估年轻成年女性的宫内发育(通过出生体重评估)和肌肉力量(通过握力评估)之间的关系。在南安普顿妇女调查中，1563名年龄在20-40岁之间的参与者在怀孕期间进行了握力测试。在招募参加调查时，这些妇女被要求回忆她们的出生体重或从父母那里获得。在南安普敦出生的536名女性的出生体重是从医院记录中获得的。通过多元线性回归分析，调整了年龄、身高、体重和报告的体力活动后，握力与出生体重有关。握力随着年龄、身高、体重、体力活动和出生体重的增加而增加。在相互调整的模型中，每公斤出生体重握力增加1.10公斤(95%可信区间：0.58至1.61公斤)。在有医院出生体重数据的妇女中，这种关系加强到每公斤出生体重1.44公斤(95%可信区间：0.50到2.38公斤)。二三十岁的女性握力达到或接近顶峰。握力和出生体重之间的联系与其他对年轻和老年女性的研究结果非常相似。这表明，子宫内发育对整个生命过程中的肌肉力量都有影响，即使考虑到肌肉力量的增加达到峰值，然后随着女性年龄的增长而下降。
To assess the relationship between development in utero, assessed by birth weight, and muscle strength in young adult women as assessed by grip strength. 1563 participants aged 20-40 years in the Southampton Women’s Survey had their grip strength measured during pregnancy. At recruitment to the Survey the women had been asked to recall their birth weight or obtain it from their parents. For 536 women born in Southampton, birth weight was obtained from hospital records. Grip strength was related to birth weight using multiple linear regression analysis, adjusting for age, height, weight and reported physical activity. Grip strength increased with age, height, weight, physical activity and birthweight. In the mutually-adjusted model, grip strength increased by 1.10kg per kg of birth weight (95%CI: 0.58 to 1.61kg). In women with hospital birth weight data the relationship strengthened to 1.44 kg per kilogram of birth weight (95%CI: 0.50 to 2.38kg). Grip strength in women in their twenties and thirties is at or approaching its peak. The association between grip strength and birthweight was remarkably similar to findings from other studies of women at younger and older ages. This indicates that in utero development has consequences for muscle strength throughout the life course, even allowing for the increase to peak muscle strength and then its decline as a woman ages.