The Effect of Presenting Information about Invasive Follow-Up Testing on Individuals' Noninvasive Colorectal Cancer Screening Participation Decision: Results from a Discrete Choice Experiment
The Effect of Presenting Information about Invasive Follow-Up Testing on Individuals' Noninvasive Colorectal Cancer Screening Participation Decision: Results from a Discrete Choice Experiment
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DOI：
10.1016/j.jval.2014.04.007
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发表时间：
2014-07-01
期刊：
影响因子：
4.5
通讯作者：
Dirksen, Carmen D.
中科院分区：
文献类型：
--
作者：
Benning, Tim M.;Dellaert, Benedict G. C.;Dirksen, Carmen D.
目的：许多国家的结直肠癌筛查活动具有相似的结构。首先，邀请个人进行非侵入性筛查测试，其次，如果筛查测试结果呈阳性，则建议他们进行更具侵入性的后续测试。本研究的目的是调查有多少个人参与无创筛查的决定是受有创性随访检测的详细信息的存在或不存在，以及这种影响如何在筛查试验中变化。研究方法：我们使用了三种非侵入性结直肠癌筛查类型的标记离散选择实验，其中有两个版本向受访者提供了或没有提供有关可能的侵入性随访测试的详细信息（即，结肠镜检查）及其程序。我们使用了631名年龄在55至75岁之间的荷兰受访者的数据。每位受访者仅收到两个版本中的一个（有创随访测试信息规范版本N = 310，无信息规范版本N = 321）。结果如下：混合logit模型的结果表明，详细信息的侵入性后续测试的负面影响筛选参与的决定。这种影响主要可以解释为最首选的筛查测试（粪便和血液样本联合测试）的选择份额减少。基于离散选择实验的选择共享模拟表明，提出侵入性随访测试信息减少筛查参与4.79%结论：侵入性随访测试的详细信息对个人在非侵入性结直肠癌筛查活动中的筛查参与决策有负面影响。这一结果对决策者提出了新的挑战，他们的目标不仅是增加吸收，而且还向潜在的筛查参与者提供充分的披露。
Objectives: Many national colorectal cancer screening campaigns have a similar structure. First, individuals are invited to take a noninvasive screening test, and, second, in the case of a positive screening test result, they are advised to undergo a more invasive follow-up test. The objective of this study was to investigate how much individuals participation decision in noninvasive screening is affected by the presence or absence of detailed information about invasive follow-up testing and how this effect varies over screening tests. Methods: We used a labeled discrete choice experiment of three noninvasive colorectal cancer screening types with two versions that did or did not present respondents with detailed information about the possible invasive follow-up test (i.e., colonoscopy) and its procedure. We used data from 631 Dutch respondents aged 55 to 75 years. Each respondent received only one of the two versions (N = 310 for the invasive follow-up test information specification version, and N = 321 for the no-information specification version). Results: Mixed logit model results show that detailed information about the invasive follow-up test negatively affects screening participation decisions. This effect can be explained mainly by a decrease in choice shares for the most preferred screening test (a combined stool and blood sample test). Choice share simulations based on the discrete choice experiment indicated that presenting invasive follow-up test information decreases screening participation by 4.79% Conclusions: Detailed information about the invasive follow-up test has a negative effect on individuals' screening participation decisions in noninvasive colorectal cancer screening campaigns. This result poses new challenges for policymakers who aim not only to increase uptake but also to provide full disclosure to potential screening participants.