Consciousness revealed: new insights into the vegetative and minimally conscious states
Consciousness revealed: new insights into the vegetative and minimally conscious states
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DOI：
10.1097/wco.0b013e32833fd4e7
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发表时间：
2010-12-01
影响因子：
4.8
通讯作者：
Owen, Adrian M.
中科院分区：
文献类型：
--
作者：
Cruse, Damian;Owen, Adrian M.
综述目的近年来，神经影像学研究的结果已经从根本上改变了我们对植物人和最低意识状态的看法。最近的发现功能磁共振成像研究表明，一些高级认知功能，如语言理解和目标检测，在一个子集的意识障碍患者保留。类似的方法甚至让一个被认为是植物人的病人也能交流。PET提供了洞察的相似性和差异的方式，疼痛是由这个病人组处理，而电生理方法揭示了进一步的证据的意识以及learning.SummaryThe预后和诊断信息提供这些新的方法清楚地表明，他们的未来使用传统的评估技术。通过证明一个行为反应迟钝的病人可以通过他/她的想法使用功能性MRI进行交流，这些新技术开辟了一个新的研究方向，开发出更复杂的通信设备，这些设备可以更普遍地被这些病人使用。在我们看来，这种设备，采用脑电图等技术，可能很快允许病人谁保留足够的认知能力进行交流，这样做的MRI扫描仪之外。
Purpose of reviewIn recent years, the results of neuroimaging studies have fundamentally changed the way we think about the vegetative and minimally conscious states.Recent findingsFunctional MRI studies have demonstrated that some high-level cognitive functions, such as language comprehension and target detection, are preserved in a subset of patients with disorders of consciousness. Similar methods have even allowed a patient who was assumed to be in a vegetative state to communicate. PET has provided insights into similarities and differences in the ways in which pain is processed by this patient group, whereas electrophysiological methods have revealed further evidence of awareness as well as learning.SummaryThe prognostic and diagnostic information provided by these new approaches clearly argues for their future use alongside conventional assessment techniques. By demonstrating that a behaviourally unresponsive patient could communicate by means of his/her thoughts using functional MRI, these new techniques open up a new direction of research into the development of more sophisticated communication devices that may be used more generally by these patients. In our opinion, such devices, employing electroencephalograph among other techniques, may soon allow for patients who retain sufficient cognitive abilities to communicate, to do so outside of an MRI scanner.