Vascular index measured by smart 3-D superb microvascular imaging can help to differentiate malignant and benign breast lesion
Vascular index measured by smart 3-D superb microvascular imaging can help to differentiate malignant and benign breast lesion
复制标题
通过智能3D微血管成像测量血管指数，有助于区分乳腺良恶性病变。
DOI：
10.2147/cmar.s203376
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发表时间：
2019-01-01
影响因子：
3.3
通讯作者：
Jiang, Yu-Xin
中科院分区：
文献类型：
--
作者：
Zhang, Xiao-Yan;Zhang, Li;Jiang, Yu-Xin
目的：我们研究的目的是前瞻性评价通过Smart 3-D超级微血管成像（SMI）测量的血管指数（VI，定义为多普勒信号像素与总病变像素之比）对乳腺病变的诊断价值。患者和方法：2016年12月至2017年11月，在北京协和医院转诊的236例乳腺病变患者连续232例纳入研究。以组织病理学结果为参考标准，计算VI的敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和准确性。结果：236例乳腺病变中，恶性121例，良性115例。恶性病变的平均VI值（9.7 +/- 8.2）明显高于良性病变（3.4 +/- 3.3）
Purpose: The purpose of our study was to prospectively evaluate the diagnostic performance of the vascular index (VI, defined as the ratio of Doppler signal pixels to pixels in the total lesion) measured via Smart 3-D superb microvascular imaging (SMI) for breast lesions.Patients and methods: Two hundred and thirty-two consecutive patients with 236 breast lesions referred for biopsy at Peking Union Medical College Hospital were enrolled in the study from December 2016 to November 2017. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of VI were calculated with histopathologic results as the reference standard.Results: Of the 236 breast lesions, 121 were malignant and 115 were benign. The mean VI was significantly higher in malignant lesions (9.7 +/- 8.2) than that in benign ones (3.4 +/- 3.3) (P