Guided web-based intervention for insomnia targeting breast cancer patients: Feasibility and effect

Guided web-based intervention for insomnia targeting breast cancer patients: Feasibility and effect
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DOI:
10.1016/j.invent.2017.03.005
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发表时间:
2017-09-01
影响因子:
4.3
通讯作者:
van Straten, Annemieke
van Straten, Annemieke
中科院分区:
医学2区
文献类型:
--
作者:
Dozeman, Els;Verdonck-de Leeuw, Irma M.;van Straten, Annemieke

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背景:乳腺癌(BRC)患者中胰岛素抵抗非常普遍,但非药物治疗并不广泛。本初步研究的目的是调查是否通过互联网(I-CBT)的指导认知行为治疗是一个可行的和有效的解决方案,这种治疗不足的条件下,在BRC patients.Methods,并调查谁受益最大:现有的证据为基础的I-CBT睡眠干预(I-Sleep)适应BRC患者。一个开放的混合方法设计,包括定性访谈和前,后测试问卷测量睡眠,疲劳,日常功能,和心理distress.Results:100的171名参与者(59%)完成了充分的干预和参与者高度重视的干预(7.5出10)。发现失眠严重程度(d = 1.33)、疲劳(d = 0.24)和日间功能(d = 0.30)的前-后效应大小从大到小。结论:I-CBT干预I-Sleep对BRC失眠患者是可行的、可接受的、有效的,尤其是对年轻患者和失眠较严重的患者。
Background: Insomnia is highly prevalent in breast cancer (BRC) patients, but non-pharmacological treatment is not widely available. The aim of this preliminary study was to investigate whether guided cognitive behavioral therapy via the Internet (I-CBT) is a feasible and effective solution for this undertreated condition in BRC patients, and to investigate who benefits most.Methods: An existing evidence based I-CBT sleep intervention (I-Sleep) was adapted for BRC patients. An open mixed methods design was used including qualitative interviews and pre- and post-test questionnaires measuring sleep, fatigue, daily functioning, and psychological distress.Results: 100 of the 171 participants (59%) completed the intervention fully and participants highly valued the intervention (7.5 out of 10). Large to small pre-post effect sizes were found on insomnia severity (d = 1.33) fatigue (d = 0.24), and daytime functioning (d = 0.30). Younger patients and patients with more severe insomnia at baseline benefited most from the intervention.Conclusion: The I-CBT intervention I-Sleep is feasible, well-accepted, and effective for BRC patients who suffer from insomnia, especially for younger patients and those with more severe insomnia.