The association of preoperative serum albumin level and American Society of Anesthesiologists (ASA) score on early complications and survival of patients undergoing radical cystectomy for urothelial bladder cancer
The association of preoperative serum albumin level and American Society of Anesthesiologists (ASA) score on early complications and survival of patients undergoing radical cystectomy for urothelial bladder cancer
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DOI：
10.1111/bju.12240
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发表时间：
2014-06-01
影响因子：
4.5
通讯作者：
Daneshmand, Siamak
中科院分区：
文献类型：
--
作者：
Djaladat, Hooman;Bruins, Harman Maxim;Daneshmand, Siamak
目的探讨术前美国麻醉医师协会（阿萨）评分和血清白蛋白水平对膀胱尿路上皮癌（UBC）根治术（RC）并发症、复发率和生存率的影响。患者和方法在1971年至2008年期间，共有1964例患者在我们的机构接受了UBC的RC。分别有1471例和1140例患者的术前血清白蛋白和阿萨评分。并发症定义为导致住院时间延长或再次入院的任何手术相关/无关事件。终点为90天并发症（90 dC）率、无复发生存期（RFS）和总生存期（OS）。结果中位（范围）随访时间为12.4（0.2-27.3）年。总的来说，197名患者（13.4%）有低白蛋白水平（
Objective To evaluate the impact of the preoperative American Society of Anesthesiologists (ASA) score and serum albumin level on complications, recurrences and survival rates of patients who underwent radical cystectomy (RC) for urothelial bladder cancer (UBC). Patients and Methods In all, 1964 patients underwent RC for UBC at our institution between 1971 and 2008. Preoperative serum albumin and ASA score were available in 1471 and 1140 patients, respectively. A complication was defined as any surgery related/unrelated event leading to lengthening hospital stay or re-admission. Endpoints were 90-day complication (90dC) rate, recurrence-free survival (RFS) and overall survival (OS). Results The median (range) follow-up was 12.4 (0.2-27.3) years. In all, 197 patients (13.4%) had a low albumin level (