Relations among psychopathology, substance use, and physical pain experiences in methadone-maintained patients.
Relations among psychopathology, substance use, and physical pain experiences in methadone-maintained patients.
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DOI：
10.4088/jcp.08m04367
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发表时间：
2009-09
期刊：
影响因子：
--
通讯作者：
Schottenfeld RS
中科院分区：
文献类型：
--
作者：
Barry DT;Beitel M;Garnet B;Joshi D;Rosenblum A;Schottenfeld RS
在美沙酮维持治疗（MMT）患者的精神痛苦和物质使用（合法和非法）的差异进行了检查，各种疼痛的经验。对目前入组MMT的150例患者的数据进行参数和非参数统计检验。与前一周报告无疼痛的MMT患者相比，患有慢性重度疼痛（CSP）的患者（即，疼痛持续至少6个月，伴有中度至重度疼痛强度或显著疼痛干扰）表现出显著更高（P < 0.01）的抑郁、焦虑、躯体化、总体精神痛苦和人格障碍标准水平，但报告了相当的物质使用率。第三组，即，非CSP MMT患者在过去一周报告了一些疼痛，与其他两个疼痛组在躯体化、焦虑和整体精神痛苦方面存在显著差异（p < 0.05），但报告了相当的物质使用率。疼痛相关的精神问题的差异存在于MMT患者，并可能有计划规划和推广工作的影响。
Differences in psychiatric distress and substance use (licit and illicit) were examined in methadone maintenance treatment (MMT) patients with a variety of pain experiences. Parametric and non-parametric statistical tests were performed on data obtained from 150 patients currently enrolled in MMT. In comparison to MMT patients reporting no pain in the previous week, those with chronic severe pain (CSP) (i.e., pain lasting at least 6 months with moderate to severe pain intensity or significant pain interference) exhibited significantly higher (p < 0.01) levels of depression, anxiety, somatization, overall psychiatric distress, and personality disorder criteria, but reported comparable rates of substance use. A third group, i.e., non-CSP MMT patients reporting some pain in the past week, differed significantly (p < 0.05) from the other two pain groups on somatization, anxiety, and global psychiatric distress but reported comparable rates of substance use. Pain-related differences in psychiatric problems exist in MMT patients and may have implications for program planning and outreach efforts.