Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial.
Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial.
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DOI：
10.3390/nu13061979
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发表时间：
2021-06-09
期刊：
影响因子：
5.9
通讯作者：
Poston L
中科院分区：
文献类型：
--
作者：
Dalrymple KV;Uwhubetine O;Flynn AC;Pasupathy D;Briley AL;Relph SA;Seed PT;O'Keeffe M;Poston L
怀孕可以改变女性整个生命过程中的体重增加轨迹，并通过保留怀孕期间增加的体重而导致肥胖的发生。本研究旨在确定 UPBEAT 研究中 667 名肥胖女性与产后体重保留（PPWR；通过怀孕前和产后 6 个月体重的差异计算）相关的可改变决定因素。我们检查了 PPWR 与报告的血糖负荷、能量摄入和妊娠期吸烟状况、妊娠期体重过度增加 (GWG)、分娩方式、自我报告的产后体力活动（低、中和高）以及婴儿喂养方式（母乳、配方奶和混合）之间的关系。在第 6 个月的访视中，48% (n = 320) 的女性体重等于或高于孕前体重。总体而言，PPWR 为负值（−0.06 kg (−42.0, 40.4)）。母乳喂养≥4个月、中度或高水平的体力活动以及GWG≤9 kg与阴性PPWR相关。这三个决定因素相结合，提供可修改的因素评分（范围 0-3）；对于每个添加的变量，与没有可改变因素的女性相比，PPWR 进一步减少了 3.0 kg（95% 置信区间 3.76，2.25）。这项研究确定了 PPWR 损失的三个附加决定因素。这些提供了怀孕期间和产后时期的可修改目标，使肥胖女性能够恢复到怀孕前的体重。
Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the difference in pre-pregnancy and 6 month postpartum weight) in 667 women with obesity from the UPBEAT study. We examined the relationship between PPWR and reported glycaemic load, energy intake, and smoking status in pregnancy, excessive gestational weight gain (GWG), mode of delivery, self-reported postpartum physical activity (low, moderate, and high), and mode of infant feeding (breast, formula, and mixed). At the 6 month visit, 48% (n = 320) of women were at or above pre-pregnancy weight. Overall, PPWR was negative (−0.06 kg (−42.0, 40.4)). Breastfeeding for ≥4 months, moderate or high levels of physical activity, and GWG ≤9 kg were associated with negative PPWR. These three determinants were combined to provide a modifiable factor score (range 0–3); for each added variable, a further reduction in PPWR of 3.0 kg (95% confidence interval 3.76, 2.25) occurred compared to women with no modifiable factors. This study identified three additive determinants of PPWR loss. These provide modifiable targets during pregnancy and the postnatal period to enable women with obesity to return to their pre-pregnancy weight.
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影响因子：
3.1
作者：
Kapinos KA;Yakusheva O;Weiss M
通讯作者：
Weiss M
影响因子：
9.8
作者：
Phelan S
通讯作者：
Phelan S
影响因子：
3.1
作者：
Briley AL;Barr S;Badger S;Bell R;Croker H;Godfrey KM;Holmes B;Kinnunen TI;Nelson SM;Oteng-Ntim E;Patel N;Robson SC;Sandall J;Sanders T;Sattar N;Seed PT;Wardle J;Poston L
通讯作者：
Poston L
DOI：
10.1038/ijo.2017.44
发表时间：
2017-07
期刊：
International journal of obesity (2005)
影响因子：
--
作者：
Patel N;Godfrey KM;Pasupathy D;Levin J;Flynn AC;Hayes L;Briley AL;Bell R;Lawlor DA;Oteng-Ntim E;Nelson SM;Robson SC;Sattar N;Singh C;Wardle J;White SL;Seed PT;Poston L
通讯作者：
Poston L
影响因子：
5.9
作者：
Dalrymple KV;Flynn AC;Relph SA;O'Keeffe M;Poston L
通讯作者：
Poston L