RAMAN STUDIES OF BOVINE SERUM-ALBUMIN

RAMAN STUDIES OF BOVINE SERUM-ALBUMIN
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DOI:
10.1002/bip.1976.360150114
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发表时间:
1976-01-01
期刊:
影响因子:
2.9
通讯作者:
KOENIG, JL
KOENIG, JL
中科院分区:
生物学4区
文献类型:
--
作者:
LIN, VJC;KOENIG, JL

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获得了牛血清白蛋白在溶质状态、碱性和酸性溶液以及凝胶中的拉曼光谱。研究了牛血清白蛋白溶液在热、酸和碱作用下的可逆变性,提出了一种新的热变性机理-α螺旋的连续去折叠。
The Raman Spectra of bovine serum albumin have been obtained in the solute state, in alkaline and acidic solutions, and in the gel. The reversible denaturations of bovine serum albumin solutions by heat, acid's, and alkali were studied and a new mechanism for heat denaturation has been proposed based on a continuous unfolding of the α‐helices.