EPIDEMIOLOGY OF CERVICAL RADICULOPATHY - A POPULATION-BASED STUDY FROM ROCHESTER, MINNESOTA, 1976 THROUGH 1990
EPIDEMIOLOGY OF CERVICAL RADICULOPATHY - A POPULATION-BASED STUDY FROM ROCHESTER, MINNESOTA, 1976 THROUGH 1990
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DOI：
10.1093/brain/117.2.325
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发表时间：
1994-04-01
期刊：
影响因子：
14.5
通讯作者：
KURLAND, LT
中科院分区：
文献类型：
--
作者：
RADHAKRISHNAN, K;LITCHY, WJ;KURLAND, LT
1976 ~ 1990年，在明尼苏达州的罗切斯特市，通过马约诊所的记录连接系统，对颈椎神经根病进行了流行病学调查，确定了561名患者（332名男性和229名女性）。年龄范围为13 - 91岁;男性的平均年龄+/-SD为47.6+/-13.1岁，女性为48.2+/-13.8岁。只有14.8%的病例在症状发作前有体力劳动或创伤史。41%的患者有腰椎神经根病既往史。诊断前症状的中位持续时间为15天。涉及C7神经根的单神经根病最常见，其次是C6。在21.9%的患者中，经证实的椎间盘突出导致颈椎神经根病; 68.4%的患者与颈椎病、椎间盘或两者相关。在平均4.9个月的随访期间，31.7%的患者复发，26%的患者接受了颈椎神经根病手术。神经根性疼痛和感觉障碍以及客观肌无力的组合是决定手术的预测因素。在最后一次随访中，我们人群中90%的患者无症状或仅因颈椎神经根病而轻度失能。罗切斯特每10万人口的平均年年龄调整后的颈椎神经根病发病率为83.2，男性为107.3，女性为63.5。50-54岁年龄组的每10万人口的年发病率达到高峰，为202.9。
An epidemiological survey of cervical radiculopathy in Rochester, Minnesota, 1976-90, through the records-linkage system of the Mayo Clinic ascertained 561 patients (332 males and 229 females). Ages ranged from 13 to 91 years; the mean age +/-SD was 47.6+/-13.1 years for males and 48.2+/-13.8 years for females. A history of physical exertion or trauma preceding the onset of symptoms occurred in only 14.8% of cases. A past history of lumbar radiculopathy was present in 41%. The median duration of symptoms prior to diagnosis was 15 days. A monoradiculopathy involving C7 nerve root was the most frequent, followed by C6. A confirmed disc protrusion was responsible for cervical radiculopathy in 21.9% of patients; 68.4% were related to spondylosis, disc or both. During the median duration of follow-up of 4.9 rears, recurrence of the condition occurred in 31.7%, and 26% underwent surgery for cervical radiculopathy. A combination of radicular pain and sensory deficit, and objective muscle weakness were predictors of a decision to operate. At last follow-up 90% of our population-based patients were asymptomatic or only mildly incapacitated due to cervical radiculopathy. The average annual age-adjusted incidence rates per 100 000 population for cervical radiculopathy in Rochester were 83.2 for the total, 107.3 for males and 63.5 for females. The age-specific annual incidence rate per 100 000 population reached a peak of 202.9 for the age group 50-54 years.