Photofrin II Pharmacokinetics and Optical Dosing in Tissue: Apparatus and Clinical Measurements for the Pharynx, Esophagus, and Tracheobronchial Tree
Photofrin II Pharmacokinetics and Optical Dosing in Tissue: Apparatus and Clinical Measurements for the Pharynx, Esophagus, and Tracheobronchial Tree
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Photofrin II 组织中的药代动力学和光学剂量：咽、食道和气管支气管树的设备和临床测量
DOI：
10.1201/9781003066897-25
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
C. Fontolliet
中科院分区：
文献类型：
--
作者：
D. Braichotte;R. Bays;G. Wagnières;A. Chátelain;C. Burckhardt;H. E. van den Bergh;P. Monnier;M. Savary;C. Fontolliet
上呼吸消化道和支气管早期癌症的光检测（可能还有光治疗）的时机和相对浓度已被优化。在患者中测量的Photofrin II的荧光组分作为静脉注射后时间的函数。在大多数情况下，测量是在肿瘤、邻近正常组织和远处皮肤上进行的。强迫症。在其它参数中，动力学将来将与早期癌症的分期，特别是与其血管化程度相关。
The timing has been optimized of photodetection (and possibly also phototherapy) of early cancer in the upper aerodigestive tract and bronchi and the relative concn. of fluorescent components of Photofrin II measured in patients as a function of the time after i.v. injection. In most cases, the measurements have been made on the tumor, neighboring normal tissue, and distant skin. The obsd. kinetics will be correlated in the future, among other parameters, with the staging of the early cancer, in particular, with its degree of vascularization.