Patients with Parkinson's disease can successfully remember to execute delayed intentions
Patients with Parkinson's disease can successfully remember to execute delayed intentions
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DOI：
10.1017/s1355617707071068
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发表时间：
2007-09-01
影响因子：
2.6
通讯作者：
Kliegel, Matthias
中科院分区：
文献类型：
--
作者：
Altgassen, Mareike;Zoellig, Jacqueline;Kliegel, Matthias
本研究调查了帕金森病（PD）患者和健康对照者的前瞻性记忆。此外，还考察了任务重要性对被试绩效的影响。实验设置要求参与者专注于未来或正在进行的任务。三个主要发现是：（1）当焦点放在前瞻记忆任务上时，PD患者在前瞻记忆任务上的表现与健康对照一样好;（2）当正在进行的活动受到压力时，他们的前瞻记忆表现受损;（3）工作记忆容量的差异与这些差异效应有关。结果表明，PD患者可以执行基于事件的前瞻性记忆任务，以正常的程度，如果前瞻性任务的组成部分是优先考虑的。数据还表明，工作记忆容量的减少在这一过程中起着重要作用。研究结果进行了讨论的概念，方法和临床意义。
The present study investigated prospective memory in patients with Parkinson's disease (PD) and healthy controls. In addition, the influence of task importance on participants' performance was examined. Experimental settings required participants to focus either on the prospective or the ongoing task. The three main findings are (1) PD patients performed as well on a prospective memory task as healthy controls when the focus was laid on the prospective memory task, (2) their prospective memory performance was impaired when the ongoing activity was stressed, and (3) differences in working memory capacity were related to these differential effects. Results indicate that PD patients can perform event-based prospective memory tasks to a normal degree if the prospective task component is prioritized. Data also suggest that a reduced working memory capacity plays an important role in this process. Findings are discussed in terms of conceptual, methodological, and clinical implications.